HFO-1234ze(E)

For HFO-1234ze(E), ashrae safety class is A2L; listing status / notes is acceptable, subject to use conditions, verified against its source on 2026-08-11.

Refrigerant: HFO-1234ze(E) verified
ASHRAE safety class: A2L verified
Listing status / notes: acceptable, subject to use conditions verified

Sourcefederalregister.gov

Verified2026-08-11

Review by2027-08-11

DatasetHVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant

What the source says

The EPA is proposing to list HCR 4141, HFO-1234ze(E), and R-516A as acceptable, subject to use conditions, for this end-use. HCR 4141 is a higher flammability refrigerant blend with each component in the A3 Safety Group. HFO-1234ze(E) and R-516A are lower flammability refrigerants, both in the A2L Safety Group.

— federalregister.gov, retrieved 2026-08-11

Source

federalregister.govhttps://www.federalregister.gov/documents/2025/11/10/2025-19812/protection-of-stratospheric-ozone-listing-of-substitutes-under-the-significant-new-alternatives

Last verified against source: 2026-08-11. Due for re-check by 2027-08-11. This page as Markdown · OKF bundle · full dataset as JSON.