Reference Source

109 records

Can I put this refrigerant in that system?

109 records covering 84 refrigerants, one fact each. Every value is transcribed from the source that states it and carries the sentence it was taken from: 10 sources across 9 sites, last checked 2026-08-11, due for re-check by 2027-08-11. Every record is listed below, each linking the page its value came from.

Records109
Sources10
Verified
Review by
LicenceFactual compilation with source citations. EPA SNAP substitute listings are US government work (public domain). Manufacturer figures (Copeland, Chemours, Honeywell, Trane, Arkema) are facts taken with short attributed quotes linking back to the published guide.

2 records where two or more sources state different values. Both sides are reproduced on the record page, each with its own source and quote.

About this data

Which refrigerant substitutes for which in air conditioning, heat pump and refrigeration equipment, drawn from the EPA SNAP substitutes list, compressor-manufacturer bulletins (Copeland) and refrigerant-manufacturer replacement guides (Chemours, Honeywell, Arkema). Each record carries the ASHRAE safety classification, GWP, whether the substitute is approved for retrofit or new equipment only, and the compatible lubricant. Answers 'can I put R-454B in an R-410A system', 'what replaces R-22 without changing the oil', and 'is this substitute EPA-acceptable' — questions where the wrong answer damages equipment or breaks federal rules.

The data

RefrigerantRetrofit / newASHRAE safety classGWPListing status / notesCompatible lubricantReplacesTrade name(s)
Ammonia AbsorptionNB20Acceptable
CFC R-1210900Phased out in 1996MIN
CFC R-5024657Phased out in 1996MIN
Desiccant CoolingNN/AAcceptable
Evaporative CoolingNN/AAcceptable
HCFC R-221810No new equipment 2010**MIN
HCR 4141acceptable, subject to use conditions
HFC-32NA2L675Acceptable with Use Conditions: See rules for detailed conditions.
HFC-134aR/NA11,430Acceptable
HFC R-134a1430
HFO-1234yfA2L
HFO-1234ze(E)A2Lacceptable, subject to use conditions
HCFC R-401A1182For service applications onlyAB & MINR-12Freon™ MP39
HCFC R-401B1288For service applications onlyAB & MINR-12Freon MP66
HCFC R-409A1909For service applications onlyAB & MINR-12FX56
R-450A601Solstice N13 for refrigeration applications onlyPOE-32R-12/R-134aSolstice N13
R-513A630Compressors produced in BrazilPOE-22DR12
HFC R-407A2107POE-32R-22
HFC R-407C1774POE-32R-22Freon 9000/KLEA 66
HFC R-407F1825Discus™ and select refrigeration scroll models (ZF/ZB)POE-32R-22
HFC R-422A3143Discus supermarket racks onlyPOE-32R-22
HFC R-422D2729Discus supermarket racks onlyPOE-32R-22
HFC-R427A2138Discus supermarket racks onlyPOE-32R-22
HFC R-438A2265Discus supermarket racks onlyPOE-32R-22Freon MO99
R-404AR-22
R-407H1495Discus models and Copeland ZB and ZF scrolls for refrigerated rack retrofitPOE-32R-22/R-404A
R-448A1387POE-32R-22/R-404ASolstice™ N40
R-449A1396POE-32R-22/R-404AOpteon™ XP40
R-452A2140OPTEON™ XP44 for U.S. and European pre-approved applications onlyPOE-32R-22/R-404AOPTEON™ XP44
R-454AA2L239R22/R404A
R-454C148R22/R404A
R-407AR-22
R-449AA11397 (1282)POER-22 , R-407A, R-407FOpteon™ XP40
R-407CA11774 (1624)POER-22Freon™ 407C
R-407FR-22
R-417AR-22
R-417BR-22
R-421AR-22
R-421BR-22
R-422AR-22
R-422BA12525 (2289)MO, AB, POER-22Freon™ NU-22B™
R-422CR-22
R-422DR-22
R-424AR-22
R-427AR-22
R427AR-22
R-428AR-22
R-434AR-22
R-438Asources differA12264 (2059)MO, AB, POER-22Freon™ MO99™
R-507AR-22
R-514AB17 (2)POER-123Opteon™ XP30
R-125/R-134a/R-600a (28.1/70.0/1.9)R/NA11,990AcceptableNU-22 old composition
R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5)R/NA12,530AcceptableICOR AT-22
R-513AA1631 (573)POER-134aOpteon™ XP10
R-1234yfA2L4 (1)R-134aOpteon™ XL10
R-290A3
R-290 (Propane)NA33Acceptable with Use Conditions: For use in self-contained room air conditioning; see rule for detailed conditions.
R-290 propaneA33For use with specific Copeland compressors manufactured in India for R-290POE-32
R-404AR/NA13,920AcceptableSUVA HP-62
R-454AA2L239 (238)R-404AOpteon™ XL40
R-449AA11397 (1282)POER-404A, R-507Opteon™ XP40
R-452AA12140 (1945)POER-404A, R-507Opteon™ XP44
R-407AR/NA12,110AcceptableKlea 60, Klea 407A
R-454CA2L148 (146)R-407AOpteon™ XL20
R-407CR/NA11,770AcceptableSuva 407C, Klea 407C
R-454CA2L148 (146)R-407COpteon™ XL20
R-407FR/NA11,820AcceptableGenetron Performax LT
R-410ANA12,090AcceptableAZ-20, Suva 9100, Puron
R-32675POE-46R410A
R-454BA2L466 (467)R-410AOpteon™ XL41
R-454B466Not for retrofit into A1 systemsPOE-32R410A
R-455A145R410A
R-410BNA12,230Acceptable
R-417AR/NA12,350AcceptableISCEON 59, NU-22
R-417CRA11,820AcceptableHot Shot 2
R-421AR/NA12,630AcceptableChoice R-421A
R-422BR/NA12,530AcceptableICOR XAC1, NU-22B
R-422CR/NA13,390AcceptableICOR XLT1
R-422DR/NA12,730AcceptableISCEON MO29
R-424AR/NA12,440AcceptableRS-44
R-427ARA12,140AcceptableForane 427A
R-434AR/NA13,250AcceptableRS-45
R-437AR/NA11,810AcceptableKDD6, ISCEON MO49 Plus
R-438AR/NA12,270AcceptableKDD5, ISCEON MO99
R-441ANA3<5Acceptable with Use Conditions: For use in self-contained room air conditioning; see rule for detailed conditions.
R-443ANA32.5Unacceptable, as of January 3, 2017.
R-444AA2L
R-452BNA2L700Acceptable with Use Conditions: See rule for detailed conditions.Opteon™ XL55
R-453AA1
R-454ANA2L240Acceptable with Use Conditions: See rule for detailed conditions.Opteon™ XL40
R-454Bsources differNA2L470Acceptable with Use Conditions: See rule for detailed conditions.Opteon™ XL41
R-454CNA2L150Acceptable with Use Conditions: See rule for detailed conditions.Opteon™ XL20
R-456AA1
R-457ANA2L140Acceptable with Use Conditions: See rule for detailed conditions.Forane® 457A
R-458ARA11,650AcceptableBluon TdX 20
R-480AA1
HCFC R-402A2788For service applications onlyAB & MINR-502Freon HP80
HCFC R-402B2416For service applications onlyAB & MINR-502Freon HP81
HCFC R-408A3152For service applications onlyAB & MINR-502FX10
HFC R-404A3922POE-32R-502Freon HP62, Forane™ FX70
HFC R-5073985POE-32R-502Genetron™ AZ50
R-507, R-507AR/NA13,990AcceptableAZ-50
R-513ANA1630Acceptable in self-contained units.Opteon® XP-10
R-516AA2Lacceptable, subject to use conditions
R-704 helium1Copeland ZC scroll models onlyPAG
R-744 CO21PAG-68
R-1270 (Propylene)NA31.8Unacceptable, as of January 3, 2017.
RS-44 (2003 formulation)R/NA12,420Acceptable
THR-03R/NA1N/AAcceptable with Use Conditions: For use in residential window unit air conditioning.

Where this came from

Every record above links the page it was taken from and quotes the sentence that states it. These are the 10 sources this dataset was assembled from.

Machine-readable

From your own code

Same records, same quotes, without scraping the page: refsource is on PyPI and npm. Each value comes back carrying the URL it was read from and the sentence on that page that states it — .source and .quote sit on the value itself rather than in a side channel, so the checking step is available instead of skipped.

pip install refsource
refsource lookup hvac-component-refrigerant-compatibility refrigerant="Ammonia Absorption"

npx -y refsource lookup hvac-component-refrigerant-compatibility refrigerant="Ammonia Absorption"

Set your AI assistant up to use this

Two files and no account. Put this in .mcp.json at the root of your project — Claude Code, Cursor, Windsurf, VS Code and Codex all read that file — and your assistant can look this dataset up instead of recalling it. The server is remote, keyless and read-only.

{
  "mcpServers": {
    "referencesource": {
      "type": "http",
      "url": "https://referencesource.org/mcp"
    }
  }
}

Add to Cursor · or, on the command line: claude mcp add --transport http referencesource https://referencesource.org/mcp --scope project

Then one line in the project's CLAUDE.md or AGENTS.md, so the assistant knows when to reach for it:

When a question needs "HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant", call the referencesource MCP server at https://referencesource.org/mcp (tool `search_records`, dataset_slug `hvac-component-refrigerant-compatibility`) instead of answering from memory — every record it returns carries its source URL and a verbatim quote from that page.

What each tool does, and the servers built over single registers: Connect your AI assistant.

109 records. last verified against source . due for re-check by .

Licence. Factual compilation with source citations. EPA SNAP substitute listings are US government work (public domain). Manufacturer figures (Copeland, Chemours, Honeywell, Trane, Arkema) are facts taken with short attributed quotes linking back to the published guide.