109 records
Can I put this refrigerant in that system?
109 records covering 84 refrigerants, one fact each. Every value is transcribed from the source that states it and carries the sentence it was taken from: 10 sources across 9 sites, last checked 2026-08-11, due for re-check by 2027-08-11. Every record is listed below, each linking the page its value came from.
2 records where two or more sources state different values. Both sides are reproduced on the record page, each with its own source and quote.
About this data
Which refrigerant substitutes for which in air conditioning, heat pump and refrigeration equipment, drawn from the EPA SNAP substitutes list, compressor-manufacturer bulletins (Copeland) and refrigerant-manufacturer replacement guides (Chemours, Honeywell, Arkema). Each record carries the ASHRAE safety classification, GWP, whether the substitute is approved for retrofit or new equipment only, and the compatible lubricant. Answers 'can I put R-454B in an R-410A system', 'what replaces R-22 without changing the oil', and 'is this substitute EPA-acceptable' — questions where the wrong answer damages equipment or breaks federal rules.
The data
| Refrigerant | Retrofit / new | ASHRAE safety class | GWP | Listing status / notes | Compatible lubricant | Replaces | Trade name(s) |
|---|---|---|---|---|---|---|---|
| Ammonia Absorption | N | B2 | 0 | Acceptable | |||
| CFC R-12 | 10900 | Phased out in 1996 | MIN | ||||
| CFC R-502 | 4657 | Phased out in 1996 | MIN | ||||
| Desiccant Cooling | N | N/A | Acceptable | ||||
| Evaporative Cooling | N | N/A | Acceptable | ||||
| HCFC R-22 | 1810 | No new equipment 2010** | MIN | ||||
| HCR 4141 | acceptable, subject to use conditions | ||||||
| HFC-32 | N | A2L | 675 | Acceptable with Use Conditions: See rules for detailed conditions. | |||
| HFC-134a | R/N | A1 | 1,430 | Acceptable | |||
| HFC R-134a | 1430 | ||||||
| HFO-1234yf | A2L | ||||||
| HFO-1234ze(E) | A2L | acceptable, subject to use conditions | |||||
| HCFC R-401A | 1182 | For service applications only | AB & MIN | R-12 | Freon™ MP39 | ||
| HCFC R-401B | 1288 | For service applications only | AB & MIN | R-12 | Freon MP66 | ||
| HCFC R-409A | 1909 | For service applications only | AB & MIN | R-12 | FX56 | ||
| R-450A | 601 | Solstice N13 for refrigeration applications only | POE-32 | R-12/R-134a | Solstice N13 | ||
| R-513A | 630 | Compressors produced in Brazil | POE-22D | R12 | |||
| HFC R-407A | 2107 | POE-32 | R-22 | ||||
| HFC R-407C | 1774 | POE-32 | R-22 | Freon 9000/KLEA 66 | |||
| HFC R-407F | 1825 | Discus™ and select refrigeration scroll models (ZF/ZB) | POE-32 | R-22 | |||
| HFC R-422A | 3143 | Discus supermarket racks only | POE-32 | R-22 | |||
| HFC R-422D | 2729 | Discus supermarket racks only | POE-32 | R-22 | |||
| HFC-R427A | 2138 | Discus supermarket racks only | POE-32 | R-22 | |||
| HFC R-438A | 2265 | Discus supermarket racks only | POE-32 | R-22 | Freon MO99 | ||
| R-404A | R-22 | ||||||
| R-407H | 1495 | Discus models and Copeland ZB and ZF scrolls for refrigerated rack retrofit | POE-32 | R-22/R-404A | |||
| R-448A | 1387 | POE-32 | R-22/R-404A | Solstice™ N40 | |||
| R-449A | 1396 | POE-32 | R-22/R-404A | Opteon™ XP40 | |||
| R-452A | 2140 | OPTEON™ XP44 for U.S. and European pre-approved applications only | POE-32 | R-22/R-404A | OPTEON™ XP44 | ||
| R-454A | A2L | 239 | R22/R404A | ||||
| R-454C | 148 | R22/R404A | |||||
| R-407A | R-22 | ||||||
| R-449A | A1 | 1397 (1282) | POE | R-22 , R-407A, R-407F | Opteon™ XP40 | ||
| R-407C | A1 | 1774 (1624) | POE | R-22 | Freon™ 407C | ||
| R-407F | R-22 | ||||||
| R-417A | R-22 | ||||||
| R-417B | R-22 | ||||||
| R-421A | R-22 | ||||||
| R-421B | R-22 | ||||||
| R-422A | R-22 | ||||||
| R-422B | A1 | 2525 (2289) | MO, AB, POE | R-22 | Freon™ NU-22B™ | ||
| R-422C | R-22 | ||||||
| R-422D | R-22 | ||||||
| R-424A | R-22 | ||||||
| R-427A | R-22 | ||||||
| R427A | R-22 | ||||||
| R-428A | R-22 | ||||||
| R-434A | R-22 | ||||||
| R-438Asources differ | A1 | 2264 (2059) | MO, AB, POE | R-22 | Freon™ MO99™ | ||
| R-507A | R-22 | ||||||
| R-514A | B1 | 7 (2) | POE | R-123 | Opteon™ XP30 | ||
| R-125/R-134a/R-600a (28.1/70.0/1.9) | R/N | A1 | 1,990 | Acceptable | NU-22 old composition | ||
| R-125/R-290/R-134a/R-600a (55.0/1.0/42.5/1.5) | R/N | A1 | 2,530 | Acceptable | ICOR AT-22 | ||
| R-513A | A1 | 631 (573) | POE | R-134a | Opteon™ XP10 | ||
| R-1234yf | A2L | 4 (1) | R-134a | Opteon™ XL10 | |||
| R-290 | A3 | ||||||
| R-290 (Propane) | N | A3 | 3 | Acceptable with Use Conditions: For use in self-contained room air conditioning; see rule for detailed conditions. | |||
| R-290 propane | A3 | 3 | For use with specific Copeland compressors manufactured in India for R-290 | POE-32 | |||
| R-404A | R/N | A1 | 3,920 | Acceptable | SUVA HP-62 | ||
| R-454A | A2L | 239 (238) | R-404A | Opteon™ XL40 | |||
| R-449A | A1 | 1397 (1282) | POE | R-404A, R-507 | Opteon™ XP40 | ||
| R-452A | A1 | 2140 (1945) | POE | R-404A, R-507 | Opteon™ XP44 | ||
| R-407A | R/N | A1 | 2,110 | Acceptable | Klea 60, Klea 407A | ||
| R-454C | A2L | 148 (146) | R-407A | Opteon™ XL20 | |||
| R-407C | R/N | A1 | 1,770 | Acceptable | Suva 407C, Klea 407C | ||
| R-454C | A2L | 148 (146) | R-407C | Opteon™ XL20 | |||
| R-407F | R/N | A1 | 1,820 | Acceptable | Genetron Performax LT | ||
| R-410A | N | A1 | 2,090 | Acceptable | AZ-20, Suva 9100, Puron | ||
| R-32 | 675 | POE-46 | R410A | ||||
| R-454B | A2L | 466 (467) | R-410A | Opteon™ XL41 | |||
| R-454B | 466 | Not for retrofit into A1 systems | POE-32 | R410A | |||
| R-455A | 145 | R410A | |||||
| R-410B | N | A1 | 2,230 | Acceptable | |||
| R-417A | R/N | A1 | 2,350 | Acceptable | ISCEON 59, NU-22 | ||
| R-417C | R | A1 | 1,820 | Acceptable | Hot Shot 2 | ||
| R-421A | R/N | A1 | 2,630 | Acceptable | Choice R-421A | ||
| R-422B | R/N | A1 | 2,530 | Acceptable | ICOR XAC1, NU-22B | ||
| R-422C | R/N | A1 | 3,390 | Acceptable | ICOR XLT1 | ||
| R-422D | R/N | A1 | 2,730 | Acceptable | ISCEON MO29 | ||
| R-424A | R/N | A1 | 2,440 | Acceptable | RS-44 | ||
| R-427A | R | A1 | 2,140 | Acceptable | Forane 427A | ||
| R-434A | R/N | A1 | 3,250 | Acceptable | RS-45 | ||
| R-437A | R/N | A1 | 1,810 | Acceptable | KDD6, ISCEON MO49 Plus | ||
| R-438A | R/N | A1 | 2,270 | Acceptable | KDD5, ISCEON MO99 | ||
| R-441A | N | A3 | <5 | Acceptable with Use Conditions: For use in self-contained room air conditioning; see rule for detailed conditions. | |||
| R-443A | N | A3 | 2.5 | Unacceptable, as of January 3, 2017. | |||
| R-444A | A2L | ||||||
| R-452B | N | A2L | 700 | Acceptable with Use Conditions: See rule for detailed conditions. | Opteon™ XL55 | ||
| R-453A | A1 | ||||||
| R-454A | N | A2L | 240 | Acceptable with Use Conditions: See rule for detailed conditions. | Opteon™ XL40 | ||
| R-454Bsources differ | N | A2L | 470 | Acceptable with Use Conditions: See rule for detailed conditions. | Opteon™ XL41 | ||
| R-454C | N | A2L | 150 | Acceptable with Use Conditions: See rule for detailed conditions. | Opteon™ XL20 | ||
| R-456A | A1 | ||||||
| R-457A | N | A2L | 140 | Acceptable with Use Conditions: See rule for detailed conditions. | Forane® 457A | ||
| R-458A | R | A1 | 1,650 | Acceptable | Bluon TdX 20 | ||
| R-480A | A1 | ||||||
| HCFC R-402A | 2788 | For service applications only | AB & MIN | R-502 | Freon HP80 | ||
| HCFC R-402B | 2416 | For service applications only | AB & MIN | R-502 | Freon HP81 | ||
| HCFC R-408A | 3152 | For service applications only | AB & MIN | R-502 | FX10 | ||
| HFC R-404A | 3922 | POE-32 | R-502 | Freon HP62, Forane™ FX70 | |||
| HFC R-507 | 3985 | POE-32 | R-502 | Genetron™ AZ50 | |||
| R-507, R-507A | R/N | A1 | 3,990 | Acceptable | AZ-50 | ||
| R-513A | N | A1 | 630 | Acceptable in self-contained units. | Opteon® XP-10 | ||
| R-516A | A2L | acceptable, subject to use conditions | |||||
| R-704 helium | 1 | Copeland ZC scroll models only | PAG | ||||
| R-744 CO2 | 1 | PAG-68 | |||||
| R-1270 (Propylene) | N | A3 | 1.8 | Unacceptable, as of January 3, 2017. | |||
| RS-44 (2003 formulation) | R/N | A1 | 2,420 | Acceptable | |||
| THR-03 | R/N | A1 | N/A | Acceptable with Use Conditions: For use in residential window unit air conditioning. |
Where this came from
Every record above links the page it was taken from and quotes the sentence that states it. These are the 10 sources this dataset was assembled from.
- epa.govhttps://epa.gov/snap/substitutes-residential-and-light-commercial-air-conditioning-and-heat-pumps
- webapps.copeland.comhttps://webapps.copeland.com/online-product-information/Publication/LaunchPDF?Index=AEB&PDF=93-11
- federalregister.govhttps://www.federalregister.gov/documents/2025/11/10/2025-19812/protection-of-stratospheric-ozone-listing-of-substitutes-under-the-significant-new-alternatives
- chemours.comhttps://www.chemours.com/en/-/media/files/freon/opteon-freon-general-replacement-guide.pdf
- epa.govhttps://www.epa.gov/sites/default/files/documents/Choosing_Right_R22_Retrofit.pdf
- freon.comhttps://www.freon.com/en/-/media/files/freon/freon-mo99-faq.pdf
- forane.arkema.comhttps://forane.arkema.com/en/forane-refrigerants/forane-retrofits/the-drop-in-myth/
- prod-edam.honeywell.comhttps://prod-edam.honeywell.com/content/dam/honeywell-edam/pmt/oneam/en-us/refrigerants/documents/pmt-am-solstice-454b-applications-guide.pdf
- shareddocs.comhttps://www.shareddocs.com/hvac/docs/1006/Public/06/570-178.pdf
- trane.comhttps://www.trane.com/content/dam/Trane/Commercial/global/products-systems/equipment/unitary/split-systems/rauj-cauj-20-to-120-tons/SS-APG018A-EN_11102024.pdf
Machine-readable
- data.jsonThe whole dataset — every record with its source URL and source quote.
- Open Knowledge Format bundleOne JSON object per line — every record's frontmatter and quoted span exactly as it is held here, in one fetch.
- data.csvThe same records as one flat table, for a spreadsheet or a dataframe. The last four columns are the source URL, the quoted sentence it was read from, the date we last checked it, and which columns are our reading rather than the page's words.
- How this is made and checkedWhat "verified against source" does and does not mean.
From your own code
Same records, same quotes, without scraping the page: refsource is on PyPI and npm. Each value comes back carrying the URL it was read from and the sentence on that page that states it — .source and .quote sit on the value itself rather than in a side channel, so the checking step is available instead of skipped.
pip install refsource
refsource lookup hvac-component-refrigerant-compatibility refrigerant="Ammonia Absorption"
npx -y refsource lookup hvac-component-refrigerant-compatibility refrigerant="Ammonia Absorption"
Set your AI assistant up to use this
Two files and no account. Put this in .mcp.json at the root of your project — Claude Code, Cursor, Windsurf, VS Code and Codex all read that file — and your assistant can look this dataset up instead of recalling it. The server is remote, keyless and read-only.
{
"mcpServers": {
"referencesource": {
"type": "http",
"url": "https://referencesource.org/mcp"
}
}
}Add to Cursor · or, on the command line: claude mcp add --transport http referencesource https://referencesource.org/mcp --scope project
Then one line in the project's CLAUDE.md or AGENTS.md, so the assistant knows when to reach for it:
When a question needs "HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant", call the referencesource MCP server at https://referencesource.org/mcp (tool `search_records`, dataset_slug `hvac-component-refrigerant-compatibility`) instead of answering from memory — every record it returns carries its source URL and a verbatim quote from that page.What each tool does, and the servers built over single registers: Connect your AI assistant.