Discovery C18 · Sigma-Aldrich / Merck
For Discovery C18, original column's brand is Sigma-Aldrich / Merck; gl sciences direct replacement is InertSustainSwift C18; gl sciences alternative is InertSustainSwift C18; bonded phase is C18; waters closest selectivity column is SunFire C8, recorded from its source on 2026-09-01; source re-checked 2026-09-30.
- Original column's brand
- Sigma-Aldrich / Merck our reading
- Original column name
- Discovery C18 verified
- GL Sciences direct replacement
- InertSustainSwift C18 verified
- GL Sciences alternative
- InertSustainSwift C18 verified
- Bonded phase
- C18 verified
- Waters closest selectivity column
- SunFire C8 verified
- Waters recommended UPLC column
- ACQUITY UPLC BEH C18 verified
- Waters recommended HPLC column
- XBridge BEH C18 XBridge BEH C18 XP verified
- Waters recommended preparative column
- XBridge BEH C18 OBD verified
Values marked our reading are our classification of what the source says — the source does not print them in those words. The quote below is the evidence for each one; judge it yourself.
What the source says
Discovery C18 | InertSustainSwift C18 View App Notes | InertSustainSwift C18 View App Notes |
— glsciencesinc.com, retrieved 2026-09-01
Where each value comes from
These values are stated in different places, and not all on the same page, so each is shown with the passage that states it and the source that passage came from.
Original column's brand
Sigma-Aldrich / Merck 68 equivalents
— from glsciencesinc.com, retrieved 2026-09-01
Bonded phase, Waters closest selectivity column, Waters recommended UPLC column, Waters recommended HPLC column and Waters recommended preparative column
Discovery C18 | C18 | SunFire C8 | ACQUITY UPLC BEH C18 | XBridge BEH C18 XBridge BEH C18 XP | XBridge BEH C18 OBD |
— from waters.com, retrieved 2026-09-01
Sources
- glsciencesinc.comhttps://www.glsciencesinc.com/hplc-column-equivalents
- waters.comhttps://www.waters.com/waters/en_US/Column-Comparison-Chart-for-UPLC,-UHPLC,-HPLC/nav.htm?cid=135047266