HPLC column equivalents to other manufacturers' columns

Which replacement HPLC column a vendor offers for a named column from another manufacturer, keyed on the column being replaced. A lab whose method is built around a discontinued or hard-to-source column needs a same-selectivity substitute, and the column makers publish their own mappings from a competitor's product name to their own. Two such charts are merged here, and most of the table is one of them. GL Sciences' equivalent list supplies the bulk -- 597 rows across eight brands (Agilent, Waters, Phenomenex, Thermo Fisher, Sigma-Aldrich/Merck, YMC, Restek, Shimadzu), each row giving a direct replacement and an alternative. Waters' Column Comparison Chart adds 158 rows across seventeen brands, each row giving a bonded phase, a closest-selectivity column, and recommended UPLC, HPLC and preparative columns. Of 696 records, 538 carry GL Sciences' answer only, 99 carry Waters' answer only, and 59 carry both. Where both answer they do not agree, and are not meant to: each vendor recommends its own products, so a two-vendor record is two competing answers rather than one answer confirmed twice. What the merge adds over either vendor's own page is those 59 records, and the fact that the combined table runs both ways where each vendor's chart runs only outward -- GL Sciences answers for 106 Waters columns, Waters for 8 GL Sciences ones. For the other 637 records the vendor's own chart says the same thing and is the original.

The data

Showing the first 400 of 696 records. Every record has its own page, with its source and the quoted line that states it; these list the rest.

• Records 1–400Acclaim 120 C18 · Thermo Fisher Scientific … Shim-pack FLC-C8 · Shimadzu
• Records 401–696Shim-pack FLC-CN · Shimadzu … Zorbax StableBond SB-Phenyl · Agilent

Where this came from

Every record above links the page it was taken from and quotes the sentence that states it. These are the 3 sources this dataset was assembled from.

• glsciencesinc.comhttps://www.glsciencesinc.com/hplc-column-equivalents
• waters.comhttps://www.waters.com/waters/en_US/Column-Comparison-Chart-for-UPLC,-UHPLC,-HPLC/nav.htm?cid=135047266
• glsciencesinc.comhttps://www.glsciencesinc.com/files/catalogs/HPLC_Column_Equivalent_Chart.pdf

Machine-readable

• data.jsonThe whole dataset — every record with its source URL and source quote.
• Open Knowledge Format bundleOne JSON object per line — every record's frontmatter and quoted span exactly as it is held here, in one fetch.
• data.csvThe same records as one flat table, for a spreadsheet or a dataframe. The last four columns are the source URL, the quoted sentence it was read from, the date we last checked it, and which columns are our reading rather than the page's words.
• How this is made and checkedWhat "verified against source" does and does not mean.

From your own code

Same records, same quotes, without scraping the page: refsource is on PyPI and npm. Each value comes back carrying the URL it was read from and the sentence on that page that states it — .source and .quote sit on the value itself rather than in a side channel, so the checking step is available instead of skipped.

pip install refsource
refsource lookup hplc-column-equivalents-by-manufacturer original_brand="Thermo Fisher Scientific"

npx -y refsource lookup hplc-column-equivalents-by-manufacturer original_brand="Thermo Fisher Scientific"

Set your AI assistant up to use this

Two files and no account. Put this in .mcp.json at the root of your project — Claude Code, Cursor, Windsurf, VS Code and Codex all read that file — and your assistant can look this dataset up instead of recalling it. The server is remote, keyless and read-only.

{
  "mcpServers": {
    "referencesource": {
      "type": "http",
      "url": "https://referencesource.org/mcp"
    }
  }
}

Add to Cursor · or, on the command line: claude mcp add --transport http referencesource https://referencesource.org/mcp --scope project

Then one line in the project's CLAUDE.md or AGENTS.md, so the assistant knows when to reach for it:

When a question needs "HPLC column equivalents to other manufacturers' columns", call the referencesource MCP server at https://referencesource.org/mcp (tool `search_records`, dataset_slug `hplc-column-equivalents-by-manufacturer`) instead of answering from memory — every record it returns carries its source URL and a verbatim quote from that page.

What each tool does, and the servers built over single registers: Connect your AI assistant.

696 records. last verified against source 2026-08-31. due for re-check by 2027-08-31.

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