# Colorado — PDMP Mandatory Prescriber Check Requirements by State

For Colorado, mandate status is mandatory; drug schedules covered is opioids, benzodiazepines; check timing is before the second fill or when exceeding short acute limits; ongoing therapy for benzodiazepines; dose escalations and combinations, recorded from its source on 2026-08-15.

- **jurisdiction:** Colorado _(verified: appears in the quote below)_
- **mandate status:** mandatory
- **drug schedules covered:** opioids, benzodiazepines
- **check timing:** before the second fill or when exceeding short acute limits; ongoing therapy for benzodiazepines; dose escalations and combinations _(verified: appears in the quote below)_

## What the source says

> Colorado: Check for opioids before the second fill or when exceeding short acute limits; benzodiazepine checks are required for ongoing therapy. Use PDMP for dose escalations and combinations.

## Source

- https://pharmacyfreak.com/pdmp-prescription-drug-monitoring-program-you-are-legally-required-to-check-the-database-but-when-the-state-by-state-rules-you-must-know/

Last verified: 2026-08-15. Review by: 2027-02-11.
Part of [PDMP Mandatory Prescriber Check Requirements by State](https://referencesource.org/pdmp-mandatory-check-requirements/).