# ISO 19290:2016 — Withdrawn and superseded ISO standards For ISO 19290:2016, item title is Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS; status code is 9599; successor is ISO 19290:2021; withdrawn / published date is 2016-11-28, recorded from its source on 2026-08-05. - **Identifier:** ISO 19290:2016 _(verified: appears in the quote below)_ - **Item title:** Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS _(verified: appears in the quote below)_ - **Status code:** 9599 _(verified: appears in the quote below)_ - **Successor:** ISO 19290:2021 - **Withdrawn / published date:** 2016-11-28 _(verified: appears in the quote below)_ ## What the source says > 64297,IS,,ISO 19290:2016,Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS,Cigarettes — Dosage des nitrosamines spécifiques du tabac dans le courant principal de fumée de cigarette — Méthode par CL-SM/SM,2016-11-28,1,['65.160'],ISO/TC 126,9599,,[81665],"['en','fr']",14,"

ISO 19290:2016 specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoana ## Source - https://isopublicstorageprod.blob.core.windows.net/opendata/_latest/iso_deliverables_metadata/csv/iso_deliverables_metadata.csv Last verified: 2026-08-05. Review by: 2027-02-01. Part of [Withdrawn and superseded ISO standards](https://referencesource.org/iso-standard-supersessions/).