# R-454C — HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant

For R-454C, replaces is R22/R404A; gwp is 148, verified against its source on 2026-08-11.

- **Refrigerant:** R-454C _(verified: appears in the quote below)_
- **Replaces:** R22/R404A _(verified: appears in the quote below)_
- **GWP:** 148 _(verified: appears in the quote below)_

## What the source says

> R-454C 148 R22/R404A – L,M

## Source

- https://webapps.copeland.com/online-product-information/Publication/LaunchPDF?Index=AEB&PDF=93-11

Last verified: 2026-08-11. Review by: 2027-08-11.
Part of [HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant](https://referencesource.org/hvac-component-refrigerant-compatibility/).