# R-454C — HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant For R-454C, replaces is R-407C; trade name(s) is Opteon™ XL20; ashrae safety class is A2L; gwp is 148 (146), verified against its source on 2026-08-11. - **Refrigerant:** R-454C _(verified: appears in the quote below)_ - **Replaces:** R-407C _(verified: appears in the quote below)_ - **Trade name(s):** Opteon™ XL20 _(verified: appears in the quote below)_ - **ASHRAE safety class:** A2L _(verified: appears in the quote below)_ - **GWP:** 148 (146) _(verified: appears in the quote below)_ ## What the source says > Opteon™ XL10 R-1234yf R-134a A2L 4 (1) -21 Opteon™ XL20 R-454C R-407C A2L 148 (146) -50 ## Source - https://www.chemours.com/en/-/media/files/freon/opteon-freon-general-replacement-guide.pdf Last verified: 2026-08-11. Review by: 2027-08-11. Part of [HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant](https://referencesource.org/hvac-component-refrigerant-compatibility/).