# R427A — HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant For R427A, replaces is R-22, verified against its source on 2026-08-11. - **Refrigerant:** R427A _(verified: appears in the quote below)_ - **Replaces:** R-22 _(verified: appears in the quote below)_ ## What the source says > Arkema recommends using Forane® 427A (R427A) - The EASY RETROFIT™ for your R-22 retrofit solution. ## Source - https://forane.arkema.com/en/forane-refrigerants/forane-retrofits/the-drop-in-myth/ Last verified: 2026-08-11. Review by: 2027-08-11. Part of [HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant](https://referencesource.org/hvac-component-refrigerant-compatibility/).