# R-507A — HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant

For R-507A, replaces is R-22, verified against its source on 2026-08-11.

- **Refrigerant:** R-507A _(verified: appears in the quote below)_
- **Replaces:** R-22 _(verified: appears in the quote below)_

## What the source says

> R-22 Retrofit Blends R-404A R-407A R-407C R-407F R-417A R-417B R-421A R-421B R-422A R-422B R-422C R-422D R-424A R-427A R-428A R-434A R-438A R-507A

## Source

- https://www.epa.gov/sites/default/files/documents/Choosing_Right_R22_Retrofit.pdf

Last verified: 2026-08-11. Review by: 2027-08-11.
Part of [HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant](https://referencesource.org/hvac-component-refrigerant-compatibility/).