# R-449A — HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant For R-449A, replaces is R-22/R-404A; trade name(s) is Opteon™ XP40; gwp is 1396; compatible lubricant is POE-32, verified against its source on 2026-08-11. - **Refrigerant:** R-449A _(verified: appears in the quote below)_ - **Replaces:** R-22/R-404A _(verified: appears in the quote below)_ - **Trade name(s):** Opteon™ XP40 _(verified: appears in the quote below)_ - **GWP:** 1396 _(verified: appears in the quote below)_ - **Compatible lubricant:** POE-32 _(verified: appears in the quote below)_ ## What the source says > R-22/R-404A L,M L,M POE-32 Opteon™ XP40 R-449A 1396 ## Source - https://webapps.copeland.com/online-product-information/Publication/LaunchPDF?Index=AEB&PDF=93-11 Last verified: 2026-08-11. Review by: 2027-08-11. Part of [HVAC refrigerant replacements: retrofit compatibility, safety class, GWP and lubricant](https://referencesource.org/hvac-component-refrigerant-compatibility/).