# THBP (2,4,5-trihydroxybutyrophenone) — Food additive regulatory approval status — US FDA vs EU

For THBP (2,4,5-trihydroxybutyrophenone), jurisdiction is US FDA (21 CFR 172–178); status is permitted; citation is 21 CFR 172.190; use conditions is antioxidant alone or in combination with other permitted antioxidants; total antioxidant content will not exceed 0.02 percent of the oil or fat content of the food, recorded from its source on 2026-08-15.

- **Additive:** THBP (2,4,5-trihydroxybutyrophenone) _(verified: appears in the quote below)_
- **Jurisdiction:** US FDA (21 CFR 172–178) _(our reading, not quoted from the source)_
- **Status:** permitted _(our reading, not quoted from the source)_
- **Citation:** 21 CFR 172.190 _(our reading, not quoted from the source)_
- **Use conditions:** antioxidant alone or in combination with other permitted antioxidants; total antioxidant content will not exceed 0.02 percent of the oil or fat content of the food

## What the source says

> The food additive THBP (2,4,5-trihydroxybutyrophenone) may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive has a melting point of 149 °C-153 °C. ( b ) It is used as an antioxidant alone or in combination with other permitted antioxidants.

## Source

- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B

Last verified: 2026-08-15. Review by: 2027-08-15.
Part of [Food additive regulatory approval status — US FDA vs EU](https://referencesource.org/food-additive-approval-status-us-vs-eu/).