# Hydroxypropyl methylcellulose — Food additive regulatory approval status — US FDA vs EU

For Hydroxypropyl methylcellulose, jurisdiction is US FDA (21 CFR 172–178); status is permitted; citation is 21 CFR 172.874; use conditions is in food, except in standardized foods which do not provide for such use if:   ( a ) The additive complies with the definition and specifications prescribed in the National Formulary, 12th edition; cas no. is 9004-65-3, recorded from its source on 2026-08-15.

- **Additive:** Hydroxypropyl methylcellulose _(verified: appears in the quote below)_
- **Jurisdiction:** US FDA (21 CFR 172–178) _(our reading, not quoted from the source)_
- **Status:** permitted _(our reading, not quoted from the source)_
- **Citation:** 21 CFR 172.874 _(our reading, not quoted from the source)_
- **Use conditions:** in food, except in standardized foods which do not provide for such use if:   ( a ) The additive complies with the definition and specifications prescribed in the National Formulary, 12th edition. _(verified: appears in the quote below)_
- **CAS No.:** 9004-65-3 _(verified: appears in the quote below)_

## What the source says

> § 172.874 Hydroxypropyl methylcellulose. The food additive hydroxypropyl methylcellulose (CAS Reg. No. 9004-65-3) may be safely used in food, except in standardized foods which do not provide for such use if: ( a ) The additive complies with the definition and specifications prescribed in the National Formulary, 12th edition.

## Source

- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172

Last verified: 2026-08-15. Review by: 2027-08-15.
Part of [Food additive regulatory approval status — US FDA vs EU](https://referencesource.org/food-additive-approval-status-us-vs-eu/).