# Folic acid (folacin) — Food additive regulatory approval status — US FDA vs EU

For Folic acid (folacin), jurisdiction is US FDA (21 CFR 172–178); status is permitted; citation is 21 CFR 172.345; use conditions is in food as a nutrient in accordance with the following prescribed conditions:   ( a ) Folic acid is the chemical N -[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- L -glutamic acid; cas no. is 59-30-3, recorded from its source on 2026-08-15.

- **Additive:** Folic acid (folacin) _(verified: appears in the quote below)_
- **Jurisdiction:** US FDA (21 CFR 172–178) _(our reading, not quoted from the source)_
- **Status:** permitted _(our reading, not quoted from the source)_
- **Citation:** 21 CFR 172.345 _(our reading, not quoted from the source)_
- **Use conditions:** in food as a nutrient in accordance with the following prescribed conditions:   ( a ) Folic acid is the chemical N -[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- L -glutamic acid. _(verified: appears in the quote below)_
- **CAS No.:** 59-30-3 _(verified: appears in the quote below)_

## What the source says

> § 172.345 Folic acid (folacin). Folic acid (CAS Reg. No. 59-30-3), also known as folacin or folate, may be safely used in food as a nutrient in accordance with the following prescribed conditions: ( a ) Folic acid is the chemical N -[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- L -glutamic acid.

## Source

- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172

Last verified: 2026-08-15. Review by: 2027-08-15.
Part of [Food additive regulatory approval status — US FDA vs EU](https://referencesource.org/food-additive-approval-status-us-vs-eu/).