# Calcium lactobionate — Food additive regulatory approval status — US FDA vs EU

For Calcium lactobionate, jurisdiction is US FDA (21 CFR 172–178); status is permitted; citation is 21 CFR 172.720; use conditions is in food in accordance with the following prescribed conditions:   ( a ) The food additive is the calcium salt of lactobionic acid (4-(β,D-galactosido)-D-gluconic acid) produced by the oxidation of lactose, recorded from its source on 2026-08-15.

- **Additive:** Calcium lactobionate _(verified: appears in the quote below)_
- **Jurisdiction:** US FDA (21 CFR 172–178) _(our reading, not quoted from the source)_
- **Status:** permitted _(our reading, not quoted from the source)_
- **Citation:** 21 CFR 172.720 _(our reading, not quoted from the source)_
- **Use conditions:** in food in accordance with the following prescribed conditions:   ( a ) The food additive is the calcium salt of lactobionic acid (4-(β,D-galactosido)-D-gluconic acid) produced by the oxidation of lactose. _(verified: appears in the quote below)_

## What the source says

> § 172.720 Calcium lactobionate. The food additive calcium lactobionate may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive is the calcium salt of lactobionic acid (4-(β,D-galactosido)-D-gluconic acid) produced by the oxidation of lactose.

## Source

- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172

Last verified: 2026-08-15. Review by: 2027-08-15.
Part of [Food additive regulatory approval status — US FDA vs EU](https://referencesource.org/food-additive-approval-status-us-vs-eu/).