# Advantame — Food additive regulatory approval status — US FDA vs EU

For Advantame, jurisdiction is US FDA (21 CFR 172–178); status is permitted; citation is 21 CFR 172.803; use conditions is as a sweetening agent and flavor enhancer in foods generally, except in meat and poultry, in accordance with current good manufacturing practice, in an amount not to exceed that reasonably required to achieve the intended technical effect, in foods for which standards of identity established unde; cas no. is 714229-20-6, recorded from its source on 2026-08-15.

- **Additive:** Advantame _(verified: appears in the quote below)_
- **Jurisdiction:** US FDA (21 CFR 172–178) _(our reading, not quoted from the source)_
- **Status:** permitted _(our reading, not quoted from the source)_
- **Citation:** 21 CFR 172.803 _(our reading, not quoted from the source)_
- **Use conditions:** as a sweetening agent and flavor enhancer in foods generally, except in meat and poultry, in accordance with current good manufacturing practice, in an amount not to exceed that reasonably required to achieve the intended technical effect, in foods for which standards of identity established unde...
- **CAS No.:** 714229-20-6 _(verified: appears in the quote below)_

## What the source says

> § 172.803 Advantame. ( a ) Advantame is the chemical N -[ N -[3-(3-hydroxy-4-methoxyphenyl)propyl]-α-aspartyl]-L-phenylalanine 1-methyl ester, monohydrate (CAS Reg. No. 714229-20-6).

## Source

- https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172

Last verified: 2026-08-15. Review by: 2027-08-15.
Part of [Food additive regulatory approval status — US FDA vs EU](https://referencesource.org/food-additive-approval-status-us-vs-eu/).