{ "name": "Food additive regulatory approval status \u2014 US FDA vs EU", "description": "Cross-jurisdictional regulatory status of food additives permitted for direct addition to food. Each record is one additive with its approval status in both the US (FDA, 21 CFR Parts 172\u2013178) and the EU (Regulation 1333/2008, Annex II). Covers whether the substance is permitted, prohibited, or conditionally restricted in each jurisdiction, with the regulatory citation and any concentration limits or use conditions. Answers 'is titanium dioxide allowed in food in the EU' (no, banned since August 2022), 'is potassium bromate permitted in the US' (yes, 21 CFR 172.730), 'which food additives are approved in the US but banned in the EU', and 'what is the E-number for sodium nitrite' (E250). The divergences are the product: BHA, BHT, TBHQ, titanium dioxide, potassium bromate, and azodicarbonamide all have different regulatory status between the US and EU, and an assistant that states one jurisdiction's position as universal is wrong for the other.", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/", "licence": "US FDA regulations are US Government works, not copyrightable. EUR-Lex content is reusable under Commission Decision 2011/833/EU. Facts are not copyrightable (Feist, 1991); each record quotes a short attributed span and links back.", "last_verified": "2026-08-15", "stale_after": "2027-08-15", "sources": [ "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B" ], "records": [ { "additive_name": "Allura red", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 129", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-allura-red", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-allura-red/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Allura red (E 129)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Carmoisine", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 122", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-carmoisine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-carmoisine/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Carmoisine (E 122)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Invertase", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Article 34", "eu_e_number": "E 1103", "id": "eu-regulation-1333-2008-annex-ii-invertase", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-invertase/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "the authorisations for E 1103 Invertase and E 1105 Lysozyme laid down in Directive 95/2/EC shall be repealed with effect from the date of application", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Konjac (E 425)", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "restricted", "regulatory_citation": "Regulation 1333/2008, Recital", "eu_e_number": "E 425", "use_conditions": "suspended for use in jelly confectionary", "id": "eu-regulation-1333-2008-annex-ii-konjac-e-425", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-konjac-e-425/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "suspending the placing on the market and import of jelly confectionary containing the food additive E 425 konjac", "verified_fields": [ "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Lysozyme", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Article 34", "eu_e_number": "E 1105", "id": "eu-regulation-1333-2008-annex-ii-lysozyme", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-lysozyme/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "the authorisations for E 1103 Invertase and E 1105 Lysozyme laid down in Directive 95/2/EC shall be repealed with effect from the date of application", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Ponceau 4R", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 124", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-ponceau-4r", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-ponceau-4r/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Ponceau 4R (E 124)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Quinoline yellow", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 104", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-quinoline-yellow", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-quinoline-yellow/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Quinoline yellow (E 104)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sunset yellow", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 110", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-sunset-yellow", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-sunset-yellow/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Sunset yellow (E 110)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Tartrazine", "jurisdiction": "EU (Regulation 1333/2008 Annex II)", "status": "permitted", "regulatory_citation": "Regulation 1333/2008, Annex V", "eu_e_number": "E 102", "use_conditions": "requires additional labelling: 'name or E number of the colour(s)': may have an adverse effect on activity and attention in children", "id": "eu-regulation-1333-2008-annex-ii-tartrazine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/eu-regulation-1333-2008-annex-ii-tartrazine/", "source": "https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32008R1333", "source_quote": "Tartrazine (E 102)", "verified_fields": [ "additive_name", "eu_e_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "1,3-Butylene glycol", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.712", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) It is prepared by the aldol condensation of acetaldehyde followed by catalytic hydrogenation.", "cas_number": "107-88-0", "id": "us-fda-21-cfr-172-178-1-3-butylene-glycol", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-1-3-butylene-glycol/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.712 1,3-Butylene glycol. The food additive 1,3-butylene glycol (CAS Reg. No. 107-88-0) may be safely used in food in accordance with the following prescribed conditions: ( a ) It is prepared by the aldol condensation of acetaldehyde followed by catalytic hydrogenation.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "4-Hydroxymethyl-2,6-di-tert-butylphenol", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.150", "use_conditions": "antioxidant alone or in combination with other permitted antioxidants; total antioxidants shall not exceed 0.02 percent of the oil or fat content of the food", "id": "us-fda-21-cfr-172-178-4-hydroxymethyl-2-6-di-tert-butylphenol", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-4-hydroxymethyl-2-6-di-tert-butylphenol/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "The food additive 4-hydroxymethyl-2,6-di- tert -butylphenol may be safely used in food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Acacia (gum arabic)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.780", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) Acacia (gum arabic) is the dried gummy exudate from stems and branches of trees of various species of the genus Acacia , family Leguminosae.", "id": "us-fda-21-cfr-172-178-acacia-gum-arabic", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-acacia-gum-arabic/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.780 Acacia (gum arabic). The food additive may be safely used in food in accordance with the following prescribed conditions: ( a ) Acacia (gum arabic) is the dried gummy exudate from stems and branches of trees of various species of the genus Acacia , family Leguminosae.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Acesulfame potassium", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.800", "use_conditions": "as a general-purpose sweetener and flavor enhancer in foods generally, except in meat and poultry, in accordance with current good manufacturing practice and in an amount not to exceed that reasonably required to accomplish the intended technical effect in foods for which standards of identity es...", "cas_number": "55589-62-3", "id": "us-fda-21-cfr-172-178-acesulfame-potassium", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-acesulfame-potassium/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] Subpart I\u2014Multipurpose Additives \u00a7 172.800 Acesulfame potassium. Acesulfame potassium (CAS Reg. No. 55589-62-3),", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Acetone peroxides", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.802", "use_conditions": "in flour, and in bread and rolls where standards of identity do not preclude its use", "id": "us-fda-21-cfr-172-178-acetone-peroxides", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-acetone-peroxides/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive acetone peroxides may be safely used in flour, and in bread and rolls where standards of identity do not preclude its use, in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Acetylated monoglycerides", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.828", "use_conditions": "in or on food", "id": "us-fda-21-cfr-172-178-acetylated-monoglycerides", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-acetylated-monoglycerides/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive acetylated monoglycerides may be safely used in or on food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Adjuvants for pesticide use dilutions", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.710", "use_conditions": "surfactants and related adjuvants added to pesticide use dilutions by grower or applicant prior to application to growing crop", "id": "us-fda-21-cfr-172-178-adjuvants-for-pesticide-use-dilutions", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-adjuvants-for-pesticide-use-dilutions/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The following surfactants and related adjuvants may be safely added to pesticide use dilutions by a grower or applicant prior to application to the growing crop", "verified_fields": [ "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Advantame", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.803", "use_conditions": "as a sweetening agent and flavor enhancer in foods generally, except in meat and poultry, in accordance with current good manufacturing practice, in an amount not to exceed that reasonably required to achieve the intended technical effect, in foods for which standards of identity established unde...", "cas_number": "714229-20-6", "id": "us-fda-21-cfr-172-178-advantame", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-advantame/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.803 Advantame. ( a ) Advantame is the chemical N -[ N -[3-(3-hydroxy-4-methoxyphenyl)propyl]-\u03b1-aspartyl]-L-phenylalanine 1-methyl ester, monohydrate (CAS Reg. No. 714229-20-6).", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Aluminum nicotinate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.310", "use_conditions": "as a source of niacin in foods for special dietary use.", "id": "us-fda-21-cfr-172-178-aluminum-nicotinate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-aluminum-nicotinate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.310 Aluminum nicotinate. Aluminum nicotinate may be safely used as a source of niacin in foods for special dietary use. A statement of the concentration of the additive, expressed as niacin, shall appear on the label of the food additive container or on that of any intermediate premix prepared therefrom.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Amino acids", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.320", "use_conditions": "as nutrients added to foods in accordance with the following conditions: ( a ) The food additive consists of one or more of the following individual amino acids in the free, hydrated, or anhydrous form, or as the hydrochloride, sodium, or potassium salts: ( 1 ) L-Alanine ( 2 ) L-Arginine ...", "id": "us-fda-21-cfr-172-178-amino-acids", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-amino-acids/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.320 Amino acids. The food additive amino acids may be safely used as nutrients added to foods in accordance with the following conditions: ( a ) The food additive consists of one or more of the following individual amino acids in the free, hydrated, or anhydrous form, or as the hydrochloride, sodium, or potassium salts:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Anoxomer", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.105", "use_conditions": "antioxidant in food at a level of not more than 5,000 parts per million based on fat and oil content of the food", "cas_number": "60837-57-2", "id": "us-fda-21-cfr-172-178-anoxomer", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-anoxomer/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.105 Anoxomer. Anoxomer as identified in this section may be safely used in accordance with the following conditions: ( a ) Anoxomer is 1,4-benzenediol, 2-(1,1-dimethylethyl)-polymer with diethenylbenzene, 4-(1,1-dimethyl-ethyl)phenol, 4- methoxyphenol, 4,4\u2032-(1-methylethylidene)bis(phenol) and 4-methylphenol (CAS Reg. No. 60837-57-2)", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Aspartame", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.804", "use_conditions": "in food in accordance with good manufacturing practice as a sweetening agent and a flavor enhancer in foods for which standards of identity established under section 401 of the Federal Food, Drug, and Cosmetic Act do not preclude such use under the following conditions: ( a ) Aspartame is the c...", "id": "us-fda-21-cfr-172-178-aspartame", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-aspartame/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.804 Aspartame. The food additive aspartame may be safely used in food in accordance with good manufacturing practice as a sweetening agent and a flavor enhancer in foods for which standards of identity established under section 401 of the Federal Food, Drug, and Cosmetic Act do not preclude such use under the following conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Azodicarbonamide", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.806", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) It is used or intended for use: ( 1 ) As an aging and bleaching ingredient in cereal flour in an amount not to exceed 2.", "id": "us-fda-21-cfr-172-178-azodicarbonamide", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-azodicarbonamide/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.806 Azodicarbonamide. The food additive azodicarbonamide may be safely used in food in accordance with the following prescribed conditions: ( a ) It is used or intended for use: ( 1 ) As an aging and bleaching ingredient in cereal flour in an amount not to exceed 2.05 grams per 100 pounds of flour (0.0045 percent; 45 parts per million).", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Bakers yeast glycan", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.898", "use_conditions": "in food in accordance with the following conditions: ( a ) Bakers yeast glycan is the comminuted, washed, pasteurized, and dried cell walls of the yeast, Saccharomyces cerevisiae.", "id": "us-fda-21-cfr-172-178-bakers-yeast-glycan", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-bakers-yeast-glycan/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "permitted for use by this section are a distinct commodity from glanded cottonseed. \u00a7 172.896 Dried yeasts. Dried yeast ( Saccharomyces cerevisiae and Saccharomyces fragilis ) and dried torula yeast ( Candida utilis ) may be safely used in food provided the total folic acid content of the yeast does not exceed 0.04 milligram per gram of yeast (approximately 0.008 milligram of pteroyglutamic acid per gram of yeast). \u00a7 172.898 Bakers yeast glycan. Bakers yeast glycan may be safely used in food in accordance with the following conditions: ( a ) Bakers yeast glycan is the comminuted, washed, pasteurized, and dried cell walls of the yeast, Saccharomyces cerevisiae. It is composed principally of long chain carbohydrates, not less than 85 percent on a dry solids basis.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Bakers yeast protein", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.325", "use_conditions": "in food in accordance with the following conditions: ( a ) Bakers yeast protein is the insoluble proteinaceous material remaining after the mechanical rupture of yeast cells of Saccharomyces cerevisiae and removal of whole cell walls by centrifugation and separation of soluble cellular materials.", "id": "us-fda-21-cfr-172-178-bakers-yeast-protein", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-bakers-yeast-protein/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.325 Bakers yeast protein. Bakers yeast protein may be safely used in food in accordance with the following conditions: ( a ) Bakers yeast protein is the insoluble proteinaceous material remaining after the mechanical rupture of yeast cells of Saccharomyces cerevisiae and removal of whole cell walls by centrifugation and separation of soluble cellular materials.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "BHA (butylated hydroxyanisole)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.110", "use_conditions": "antioxidant in foods, alone or in combination with BHT; limits vary by food (e.g. 50 ppm in dehydrated potato shreds, 1,000 ppm in active dry yeast)", "id": "us-fda-21-cfr-172-178-bha-butylated-hydroxyanisole", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-bha-butylated-hydroxyanisole/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.110 BHA. The food additive BHA (butylated hydroxyanisole) alone or in combination with other antioxidants permitted in food for human consumption in this subpart B may be safely used in or on specified foods", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "BHT (butylated hydroxytoluene)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.115", "use_conditions": "antioxidant in foods, alone or in combination with BHA; limits vary by food (e.g. 50 ppm in dehydrated potato shreds, 200 ppm in emulsion stabilizers for shortenings)", "id": "us-fda-21-cfr-172-178-bht-butylated-hydroxytoluene", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-bht-butylated-hydroxytoluene/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.115 BHT. The food additive BHT (butylated hydroxytoluene), alone or in combination with other antioxidants permitted in this subpart B may be safely used in or on specified foods", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium disodium EDTA", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.120", "use_conditions": "preservative and color retention agent in various canned foods, dressings, and beverages; limits vary by food (e.g. 33 ppm in canned carbonated soft drinks, 75 ppm in mayonnaise, 800 ppm in processed dry pinto beans)", "id": "us-fda-21-cfr-172-178-calcium-disodium-edta", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-disodium-edta/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.120 Calcium disodium EDTA. The food additive calcium disodium EDTA (calcium disodium ethylene-diaminetetraacetate) may be safely used in designated foods for the purposes and in accordance with the conditions prescribed", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium lactobionate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.720", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is the calcium salt of lactobionic acid (4-(\u03b2,D-galactosido)-D-gluconic acid) produced by the oxidation of lactose.", "id": "us-fda-21-cfr-172-178-calcium-lactobionate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-lactobionate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.720 Calcium lactobionate. The food additive calcium lactobionate may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive is the calcium salt of lactobionic acid (4-(\u03b2,D-galactosido)-D-gluconic acid) produced by the oxidation of lactose.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium lignosulfonate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.715", "use_conditions": "in or on food, subject to the provisions of this section.", "id": "us-fda-21-cfr-172-178-calcium-lignosulfonate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-lignosulfonate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] \u00a7 172.715 Calcium lignosulfonate. Calcium lignosulfonate may be safely used in or on food, subject to the provisions of this section. ( a ) Calcium lignosulfonate consists of sulfonated lignin, primarily as calcium and sodium salts.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium pantothenate, calcium chloride double salt", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.330", "use_conditions": "in foods for special dietary uses in accordance with good manufacturing practice and under the following prescribed conditions: ( a ) The food additive is of the d (dextrorotatory) or the dl (racemic) form.", "id": "us-fda-21-cfr-172-178-calcium-pantothenate-calcium-chloride-double-salt", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-pantothenate-calcium-chloride-double-salt/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.330 Calcium pantothenate, calcium chloride double salt. The food additive calcium chloride double salt of calcium pantothenate may be safely used in foods for special dietary uses in accordance with good manufacturing practice and under the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium silicate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.410", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) It is used as an anticaking agent in food in an amount not in excess of that reasonably required to produce its intended effect.", "id": "us-fda-21-cfr-172-178-calcium-silicate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-silicate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.410 Calcium silicate. Calcium silicate, including synthetic calcium silicate, may be safely used in food in accordance with the following prescribed conditions: ( a ) It is used as an anticaking agent in food in an amount not in excess of that reasonably required to produce its intended effect.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Calcium stearoyl-2-lactylate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.844", "use_conditions": "in or on food", "id": "us-fda-21-cfr-172-178-calcium-stearoyl-2-lactylate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-calcium-stearoyl-2-lactylate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive calcium stearoyl-2-lactylate may be safely used in or on food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Carrageenan", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.620", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is the refined hydrocolloid prepared by aqueous extraction from the following members of the families Gigartinaceae and Solieriaceae of the class Rodophyceae (red seaweed): Chondrus crispus.", "id": "us-fda-21-cfr-172-178-carrageenan", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-carrageenan/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.620 Carrageenan. The food additive carrageenan may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive is the refined hydrocolloid prepared by aqueous extraction from the following members of the families Gigartinaceae and Solieriaceae of the class Rodophyceae (red seaweed):", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Carrageenan with polysorbate 80", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.623", "id": "us-fda-21-cfr-172-178-carrageenan-with-polysorbate-80", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-carrageenan-with-polysorbate-80/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.623 Carrageenan with polysorbate 80. Carrageenan otherwise meeting the definition and specifications of ", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Castor oil", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.876", "use_conditions": "in accordance with the following conditions: ( a ) The additive meets the specifications of the United States Pharmacopeia XX (1980).", "id": "us-fda-21-cfr-172-178-castor-oil", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-castor-oil/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.876 Castor oil. The food additive castor oil may be safely used in accordance with the following conditions: ( a ) The additive meets the specifications of the United States Pharmacopeia XX (1980). ( b ) The additive is used or intended for use as follows:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Coatings on fresh citrus fruit", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.210", "id": "us-fda-21-cfr-172-178-coatings-on-fresh-citrus-fruit", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-coatings-on-fresh-citrus-fruit/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.210 Coatings on fresh citrus fruit. Coatings may be applied to fresh citrus fruit for protection of the fruit in accordance with the following conditions: ( a ) The coating is applied in the minimum amount required to accomplish the intended effect.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Cocoa butter substitute from coconut oil, palm kernel oil, or both oils", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.861", "use_conditions": "in food in accordance with the following conditions: ( a ) Cocoa butter substitute from coconut oil, palm kernel oil (CAS Reg.", "cas_number": "85665-33-4", "id": "us-fda-21-cfr-172-178-cocoa-butter-substitute-from-coconut-oil-palm-kernel-oil-or-both-oils", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-cocoa-butter-substitute-from-coconut-oil-palm-kernel-oil-or-both-oils/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive, cocoa butter substitute from coconut oil, palm kernel oil, or both oils, may be safely used in food in accordance with the following conditions: ( a ) Cocoa butter substitute from coconut oil, palm kernel oil (CAS Reg. No. 85665-33-4), or both oils is a mixture of triglycerides.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Cocoa with dioctyl sodium sulfosuccinate for manufacturing", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.520", "id": "us-fda-21-cfr-172-178-cocoa-with-dioctyl-sodium-sulfosuccinate-for-manufacturing", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-cocoa-with-dioctyl-sodium-sulfosuccinate-for-manufacturing/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.520 Cocoa with dioctyl sodium sulfosuccinate for manufacturing. The food additive \u201ccocoa with dioctyl sodium sulfosuccinate for manufacturing,\u201d conforming to \u00a7 163.117 of this chapter and ", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Copolymer condensates of ethylene oxide and propylene oxide", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.808", "use_conditions": "in food under the following prescribed conditions: ( a ) The additive consists of one of the following: ( 1 ) \u03b1-Hydro- omega -hydroxy-poly (oxyethylene) poly(oxypropylene)-(55-61 moles)poly(oxyethylene) block copolymer, having a molecular weight range of 9,760-13,200 and a cloud point above 1...", "id": "us-fda-21-cfr-172-178-copolymer-condensates-of-ethylene-oxide-and-propylene-oxide", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-copolymer-condensates-of-ethylene-oxide-and-propylene-oxide/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.808 Copolymer condensates of ethylene oxide and propylene oxide. Copolymer condensates of ethylene oxide and propylene oxide may be safely used in food under the following prescribed conditions: ( a ) The additive consists of one of the following:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Coumarone-indene resin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.215", "use_conditions": "on grapefruit, lemons, limes, oranges, tangelos, and tangerines in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by the polymerization of a crude, heavy coal-tar solvent naphtha meeting the following specifications: ( 1 ) It is a mixture of inden...", "id": "us-fda-21-cfr-172-178-coumarone-indene-resin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-coumarone-indene-resin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.215 Coumarone-indene resin. The food additive coumarone-indene resin may be safely used on grapefruit, lemons, limes, oranges, tangelos, and tangerines in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by the polymerization of a crude, heavy coal-tar solvent naphtha meeting the following specifications:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Curdlan", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.809", "use_conditions": "in accordance with the following conditions: ( a ) Curdlan is a high molecular weight polymer of glucose (\u03b2-1,3-glucan; CAS Reg.", "cas_number": "54724-00-4", "id": "us-fda-21-cfr-172-178-curdlan", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-curdlan/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.809 Curdlan. Curdlan may be safely used in accordance with the following conditions: ( a ) Curdlan is a high molecular weight polymer of glucose (\u03b2-1,3-glucan; CAS Reg. No. 54724-00-4) produced by pure culture fermentation from the nonpathogenic and nontoxicogenic bacterium Alcaligenes faecalis var. myxogenes.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "D-Pantothenamide", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.335", "use_conditions": "in foods for special dietary use in an amount not in excess of that reasonably required to produce its intended effect.", "id": "us-fda-21-cfr-172-178-d-pantothenamide", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-d-pantothenamide/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.335 D-Pantothenamide. The food additive D-pantothenamide as a source of pantothenic acid activity, may be safely used in foods for special dietary use in an amount not in excess of that reasonably required to produce its intended effect.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Dehydroacetic acid", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.130", "use_conditions": "preservative for cut or peeled squash, no more than 65 parts per million expressed as dehydroacetic acid remains in or on the prepared squash", "id": "us-fda-21-cfr-172-178-dehydroacetic-acid", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-dehydroacetic-acid/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "Permitted for Direct Addition to Food for Human Consumption Subpart B Previous Next Top Table of Contents Enhanced Content - Table of Contents Subpart B | Food Preservatives | 172.105 \u2013 172.190 | \u00a7 172.105 | Anoxomer. | \u00a7 172.110 | BHA. | \u00a7 172.115 | BHT. | \u00a7 172.120 | Calcium disodium EDTA. | \u00a7 172.130 | Dehydroacetic acid.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Dimethyl dicarbonate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.133", "use_conditions": "microbial control agent in wine (not to exceed 200 ppm), ready-to-drink teas (not to exceed 250 ppm), carbonated dilute beverages containing juice (not to exceed 250 ppm), and electrolyte beverages (not to exceed 250 ppm)", "cas_number": "4525-33-1", "id": "us-fda-21-cfr-172-178-dimethyl-dicarbonate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-dimethyl-dicarbonate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.133 Dimethyl dicarbonate. Dimethyl dicarbonate (CAS Reg. No. 4525-33-1) may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Disodium EDTA", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.135", "use_conditions": "preservative and color retention in canned foods, dressings, sauces; limits vary by food (e.g. 75 ppm in mayonnaise, 500 ppm in canned strawberry pie filling, 36 ppm in cooked sausage as cure accelerator)", "id": "us-fda-21-cfr-172-178-disodium-edta", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-disodium-edta/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.135 Disodium EDTA. The food additive disodium EDTA (disodium ethylenediaminetetraacetate) may be safely used in designated foods for the purposes and in accordance with the following prescribed conditions", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Disodium guanylate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.530", "use_conditions": "as a flavor enhancer in foods, at a level not in excess of that reasonably required to produce the intended effect.", "id": "us-fda-21-cfr-172-178-disodium-guanylate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-disodium-guanylate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.530 Disodium guanylate. Disodium guanylate may be safely used as a flavor enhancer in foods, at a level not in excess of that reasonably required to produce the intended effect.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Disodium inosinate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.535", "use_conditions": "flavor enhancer", "id": "us-fda-21-cfr-172-178-disodium-inosinate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-disodium-inosinate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive disodium inosinate may be safely used in food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "DL-Alanine", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.540", "use_conditions": "as a flavor enhancer for sweeteners in pickling mixtures at a level not to exceed 1 percent of the pickling spice that is added to the pickling brine.", "cas_number": "302-72-7", "id": "us-fda-21-cfr-172-178-dl-alanine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-dl-alanine/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.540 DL-Alanine. DL-Alanine (a racemic mixture of D- and L-alanine; CAS Reg. No. 302-72-7) may be safely used as a flavor enhancer for sweeteners in pickling mixtures at a level not to exceed 1 percent of the pickling spice that is added to the pickling brine.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Dried yeasts", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.896", "use_conditions": "in food provided the total folic acid content of the yeast does not exceed 0.", "id": "us-fda-21-cfr-172-178-dried-yeasts", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-dried-yeasts/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.896 Dried yeasts. Dried yeast ( Saccharomyces cerevisiae and Saccharomyces fragilis ) and dried torula yeast ( Candida utilis ) may be safely used in food provided the total folic acid content of the yeast does not exceed 0.04 milligram per gram of yeast (approximately 0.008 milligram of pteroyglutamic acid per gram of yeast).", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Epoxidized soybean oil", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.723", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The additive is prepared by reacting soybean oil in toluene with hydrogen peroxide and formic acid.", "id": "us-fda-21-cfr-172-178-epoxidized-soybean-oil", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-epoxidized-soybean-oil/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.723 Epoxidized soybean oil. Epoxidized soybean oil may be safely used in accordance with the following prescribed conditions: ( a ) The additive is prepared by reacting soybean oil in toluene with hydrogen peroxide and formic acid. ( b ) It meets the following specifications:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Ethoxylated mono- and diglycerides", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.834", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by: ( 1 ) Glycerolysis of edible fats primarily composed of stearic, palmitic, and myristic acids; or ( 2 ) Direct esterification of glycerol with a mixture of primarily stearic, palmitic...", "id": "us-fda-21-cfr-172-178-ethoxylated-mono-and-diglycerides", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-ethoxylated-mono-and-diglycerides/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.834 Ethoxylated mono- and diglycerides. The food additive ethoxylated mono-and diglycerides (polyoxyethylene (20) mono- and diglycerides of fatty acids) (polyglycerate 60) may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Ethoxyquin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.140", "use_conditions": "antioxidant for preservation of color in chili powder, paprika, and ground chili at levels not in excess of 100 parts per million", "id": "us-fda-21-cfr-172-178-ethoxyquin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-ethoxyquin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.140 Ethoxyquin. ( a ) Ethoxyquin (1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline) may be safely used as an antioxidant for preservation of color in the production of chili powder, paprika, and ground chili at levels not in excess of 100 parts per million.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Ethyl cellulose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.868", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is a cellulose ether containing ethoxy (OC 2 H 5 ) groups attached by an ether linkage and containing on an anhydrous basis not more than 2.", "id": "us-fda-21-cfr-172-178-ethyl-cellulose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-ethyl-cellulose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.868 Ethyl cellulose. The food additive ethyl cellulose may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive is a cellulose ether containing ethoxy (OC 2 H 5 ) groups attached by an ether linkage and containing on an anhydrous basis not more than 2.6 ethoxy groups per anhydroglucose unit.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Ethylene oxide polymer", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.770", "use_conditions": "as a foam stabilizer in fermented malt beverages in accordance with the following conditions.", "id": "us-fda-21-cfr-172-178-ethylene-oxide-polymer", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-ethylene-oxide-polymer/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.770 Ethylene oxide polymer. The polymer of ethylene oxide may be safely used as a foam stabilizer in fermented malt beverages in accordance with the following conditions. ( a ) It is the polymer of ethylene oxide having a minimum viscosity of 1,500 centipoises in a 1 percent aqueous solution at 25 \u00b0C.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Fish protein isolate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.340", "use_conditions": "as a food supplement in accordance with the following prescribed conditions: ( 1 ) The additive shall consist principally of dried fish protein prepared from the edible portions of fish after removal of the heads, fins, tails, bones, scales, viscera, and intestinal contents.", "id": "us-fda-21-cfr-172-178-fish-protein-isolate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-fish-protein-isolate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.340 Fish protein isolate. ( a ) The food additive fish protein isolate may be safely used as a food supplement in accordance with the following prescribed conditions: ( 1 ) The additive shall consist principally of dried fish protein prepared from the edible portions of fish after removal of the heads, fins, tails, bones, scales, viscera, and intestinal contents.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Folic acid (folacin)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.345", "use_conditions": "in food as a nutrient in accordance with the following prescribed conditions: ( a ) Folic acid is the chemical N -[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- L -glutamic acid.", "cas_number": "59-30-3", "id": "us-fda-21-cfr-172-178-folic-acid-folacin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-folic-acid-folacin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.345 Folic acid (folacin). Folic acid (CAS Reg. No. 59-30-3), also known as folacin or folate, may be safely used in food as a nutrient in accordance with the following prescribed conditions: ( a ) Folic acid is the chemical N -[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- L -glutamic acid.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Food starch-modified", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.892", "use_conditions": "in food.", "id": "us-fda-21-cfr-172-178-food-starch-modified", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-food-starch-modified/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.892 Food starch-modified. Food starch-modified as described in this section may be safely used in food.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Fumaric acid and salts of fumaric acid", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.350", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additives meet the following specifications: ( 1 ) Fumaric acid contains a minimum of 99.", "id": "us-fda-21-cfr-172-178-fumaric-acid-and-salts-of-fumaric-acid", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-fumaric-acid-and-salts-of-fumaric-acid/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.350 Fumaric acid and salts of fumaric acid. Fumaric acid and its calcium, ferrous, magnesium, potassium, and sodium salts may be safely used in food in accordance with the following prescribed conditions: ( a ) The additives meet the following specifications:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Furcelleran", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.655", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is the refined hydrocolloid prepared by aqueous extraction of furcellaria fastigiata of the class Rodophyceae (red seaweed).", "id": "us-fda-21-cfr-172-178-furcelleran", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-furcelleran/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.655 Furcelleran. The food additive furcelleran may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive is the refined hydrocolloid prepared by aqueous extraction of furcellaria fastigiata of the class Rodophyceae (red seaweed).", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Gellan gum", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.665", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is a high molecular weight polysaccharide gum produced from Pseudomonas elodea by a pure culture fermentation process and purified by recovery with isopropyl alcohol.", "id": "us-fda-21-cfr-172-178-gellan-gum", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-gellan-gum/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive gellan gum may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is a high molecular weight polysaccharide gum produced from Pseudomonas elodea by a pure culture fermentation process and purified by recovery with isopropyl alcohol.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Gibberellic acid and its potassium salt", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.725", "id": "us-fda-21-cfr-172-178-gibberellic-acid-and-its-potassium-salt", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-gibberellic-acid-and-its-potassium-salt/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.725 Gibberellic acid and its potassium salt. The food additives gibberellic acid and its potassium salt may be used in the malting of barley in accordance with the following prescribed conditions: ( a ) The additives meet the following specifications:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Glycerides and polyglycides of hydrogenated vegetable oils", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.736", "use_conditions": "in food", "id": "us-fda-21-cfr-172-178-glycerides-and-polyglycides-of-hydrogenated-vegetable-oils", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-glycerides-and-polyglycides-of-hydrogenated-vegetable-oils/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive glycerides and polyglycides of hydrogenated vegetable oils may be safely used in food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Glycerol ester of rosin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.735", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) It has an acid number of 3 to 9, a drop-softening point of 88 to 96 \u00b0C; and a color of N or paler as determined in accordance with Official Naval Stores Standards of the United States.", "id": "us-fda-21-cfr-172-178-glycerol-ester-of-rosin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-glycerol-ester-of-rosin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.735 Glycerol ester of rosin. Glycerol ester of wood rosin, gum rosin, or tall oil rosin may be safely used in food in accordance with the following prescribed conditions: ( a ) It has an acid number of 3 to 9, a drop-softening point of 88 to 96 \u00b0C; and a color of N or paler as determined in accordance with Official Naval Stores Standards of the United States. It is purified by countercurrent steam distillation or steam stripping.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Glyceryl-lacto esters of fatty acids", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.852", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) They are manufactured from glycerin, lactic acid, and fatty acids conforming with ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Glyceryl tristearate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.811", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive (CAS Reg.", "cas_number": "555-43-1", "id": "us-fda-21-cfr-172-178-glyceryl-tristearate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-glyceryl-tristearate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.811 Glyceryl tristearate. The food additive glyceryl tristearate may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive (CAS Reg. No. 555-43-1) is prepared by reacting stearic acid with glycerol in the presence of a suitable catalyst.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Glycine", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.812", "use_conditions": "for technological purposes in food in accordance with the following prescribed conditions: ( a ) The additive meets the specifications of the Food Chemicals Codex, 7th ed.", "id": "us-fda-21-cfr-172-178-glycine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-glycine/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Glycine. The food additive glycine may be safely used for technological purposes in food in accordance with the following prescribed conditions: ( a ) The additive meets the specifications of the Food Chemicals Codex, 7th ed. (2010), pp.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Heptylparaben", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.145", "use_conditions": "antimicrobial in fermented malt beverages (not to exceed 12 ppm) and in noncarbonated soft drinks and fruit-based beverages (not to exceed 20 ppm)", "id": "us-fda-21-cfr-172-178-heptylparaben", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-heptylparaben/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.145 Heptylparaben. ( a ) The food additive heptylparaben is the chemical n -heptyl p -hydroxybenzoate. ( b ) It may be safely used to inhibit microbiological spoilage in accordance with the following prescribed conditions: ( 1 ) In fermented malt beverages in amounts not to exceed 12 parts per million.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Hydroxylated lecithin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.814", "use_conditions": "as an emulsifier in foods in accordance with the following conditions: ( a ) The additive is obtained by the treatment of lecithin in one of the following ways, under controlled conditions whereby the separated fatty acid fraction of the resultant product has an acetyl value of 30 to 38: ( 1 ...", "id": "us-fda-21-cfr-172-178-hydroxylated-lecithin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-hydroxylated-lecithin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.814 Hydroxylated lecithin. The food additive hydroxylated lecithin may be safely used as an emulsifier in foods in accordance with the following conditions: ( a ) The additive is obtained by the treatment of lecithin in one of the following ways, under controlled conditions whereby the separated fatty acid fraction of the resultant product has an acetyl value of 30 to 38:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Hydroxypropyl cellulose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.870", "use_conditions": "in food, except standardized foods that do not provide for such use, in accordance with the following prescribed conditions: ( a ) The additive consists of one of the following: ( 1 ) A cellulose ether containing propylene glycol groups attached by an ether linkage that contains, on an anhydr...", "id": "us-fda-21-cfr-172-178-hydroxypropyl-cellulose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-hydroxypropyl-cellulose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.870 Hydroxypropyl cellulose. The food additive hydroxypropyl cellulose may be safely used in food, except standardized foods that do not provide for such use, in accordance with the following prescribed conditions: ( a ) The additive consists of one of the following:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Hydroxypropyl methylcellulose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.874", "use_conditions": "in food, except in standardized foods which do not provide for such use if: ( a ) The additive complies with the definition and specifications prescribed in the National Formulary, 12th edition.", "cas_number": "9004-65-3", "id": "us-fda-21-cfr-172-178-hydroxypropyl-methylcellulose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-hydroxypropyl-methylcellulose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.874 Hydroxypropyl methylcellulose. The food additive hydroxypropyl methylcellulose (CAS Reg. No. 9004-65-3) may be safely used in food, except in standardized foods which do not provide for such use if: ( a ) The additive complies with the definition and specifications prescribed in the National Formulary, 12th edition.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Iron ammonium citrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.430", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is the chemical green ferric ammonium citrate.", "id": "us-fda-21-cfr-172-178-iron-ammonium-citrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-iron-ammonium-citrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.430 Iron ammonium citrate. Iron ammonium citrate may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is the chemical green ferric ammonium citrate.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Iron-choline citrate complex", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.370", "use_conditions": "as a source of iron in foods for special dietary use.", "id": "us-fda-21-cfr-172-178-iron-choline-citrate-complex", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-iron-choline-citrate-complex/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.370 Iron-choline citrate complex. Iron-choline citrate complex made by reacting approximately equimolecular quantities of ferric hydroxide, choline, and citric acid may be safely used as a source of iron in foods for special dietary use.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Kelp", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.365", "use_conditions": "source of essential mineral iodine; maximum intake shall not exceed 225 micrograms of iodine daily", "id": "us-fda-21-cfr-172-178-kelp", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-kelp/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Kelp may be safely added to a food as a source of the essential mineral iodine, provided the maximum intake of the food as may be consumed during a period of one day, or as directed for use in the cas", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Lactylated fatty acid esters of glycerol and propylene glycol", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.850", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is a mixture of esters produced by the lactylation of a product obtained by reacting edible fats or oils with propylene glycol.", "id": "us-fda-21-cfr-172-178-lactylated-fatty-acid-esters-of-glycerol-and-propylene-glycol", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-lactylated-fatty-acid-esters-of-glycerol-and-propylene-glycol/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.850 Lactylated fatty acid esters of glycerol and propylene glycol. The food additive lactylated fatty acid esters of glycerol and propylene glycol may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is a mixture of esters produced by the lactylation of a product obtained by reacting edible fats or oils with propylene glycol.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Lactylic esters of fatty acids", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.848", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) They are prepared from lactic acid and fatty acids meeting the requirements of ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Listeria -specific bacteriophage preparation", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.785", "use_conditions": "as an antimicrobial agent specific for Listeria monocytogenes ( L.", "id": "us-fda-21-cfr-172-178-listeria-specific-bacteriophage-preparation", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-listeria-specific-bacteriophage-preparation/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] \u00a7 172.785 Listeria -specific bacteriophage preparation. The additive may be safely used as an antimicrobial agent specific for Listeria monocytogenes ( L. monocytogenes ) in accordance with the following conditions:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Methacrylic acid-divinylbenzene copolymer", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.775", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is produced by the polymerization of methacrylic acid and divinylbenzene.", "id": "us-fda-21-cfr-172-178-methacrylic-acid-divinylbenzene-copolymer", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-methacrylic-acid-divinylbenzene-copolymer/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.775 Methacrylic acid-divinylbenzene copolymer. Methacrylic acid-divinylbenzene copolymer may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is produced by the polymerization of methacrylic acid and divinylbenzene. The divinylbenzene functions as a cross-linking agent and constitutes a minimum of 4 percent of the polymer.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Methyl and ethyl esters of fatty acids produced from edible fats and oils", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.225", "use_conditions": "in food, subject to the following prescribed conditions: ( a ) The additive consists of a mixture of either methyl or ethyl esters of fatty acids produced from edible fats and oils and meets the following specifications: ( 1 ) Not less than 90 percent methyl or ethyl esters of fatty acids.", "id": "us-fda-21-cfr-172-178-methyl-and-ethyl-esters-of-fatty-acids-produced-from-edible-fats-and-oils", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-methyl-and-ethyl-esters-of-fatty-acids-produced-from-edible-fats-and-oils/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "19, 1984] \u00a7 172.225 Methyl and ethyl esters of fatty acids produced from edible fats and oils. Methyl esters and ethyl esters of fatty acids produced from edible fats and oils may be safely used in food, subject to the following prescribed conditions: ( a ) The additive consists of a mixture of either methyl or ethyl esters of fatty acids produced from edible fats and oils and meets the following specifications: ( 1 ) Not less than 90 percent methyl or ethyl esters of fatty acids. ( 2 ) Not more than 1.5 percent unsaponifiable matter.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Methyl ethyl cellulose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.872", "use_conditions": "in food in accordance with the following prescribed conditions.", "id": "us-fda-21-cfr-172-178-methyl-ethyl-cellulose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-methyl-ethyl-cellulose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "9, 1981, as amended at 76 FR 41689 , July 15, 2011] \u00a7 172.872 Methyl ethyl cellulose. The food additive methyl ethyl cellulose may be safely used in food in accordance with the following prescribed conditions.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Methyl glucoside-coconut oil ester", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.816", "use_conditions": "in food in accordance with the following conditions: ( a ) It is the methyl glucoside-coconut oil ester having the following specifications: Acid number: 10-20 Hydroxyl number: 200-300 pH (5% aqueous): 4.", "id": "us-fda-21-cfr-172-178-methyl-glucoside-coconut-oil-ester", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-methyl-glucoside-coconut-oil-ester/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.816 Methyl glucoside-coconut oil ester. Methyl glucoside-coconut oil ester may be safely used in food in accordance with the following conditions: ( a ) It is the methyl glucoside-coconut oil ester having the following specifications: Acid number: 10-20", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Microcapsules for flavoring substances", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.230", "use_conditions": "for encapsulating discrete particles of flavoring substances that are generally recognized as safe for their intended use or are regulated under this part, in accordance with the following conditions: ( a ) The microcapsules may be formulated from the following components, each used in the mini...", "id": "us-fda-21-cfr-172-178-microcapsules-for-flavoring-substances", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-microcapsules-for-flavoring-substances/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.230 Microcapsules for flavoring substances. Microcapsules may be safely used for encapsulating discrete particles of flavoring substances that are generally recognized as safe for their intended use or are regulated under this part, in accordance with the following conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Modified cottonseed products intended for human consumption", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.894", "id": "us-fda-21-cfr-172-178-modified-cottonseed-products-intended-for-human-consumption", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-modified-cottonseed-products-intended-for-human-consumption/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.894 Modified cottonseed products intended for human consumption. The food additive modified cottonseed products may be used for human consumption in accordance with the following prescribed conditions: ( a ) The additive is derived from: ( 1 ) Decorticated, partially defatted, cooked, ground cottonseed kernels; or", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Modified hop extract", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.560", "use_conditions": "in beer in accordance with the following prescribed conditions: ( a ) The food additive is used or intended for use as a flavoring agent in the brewing of beer.", "id": "us-fda-21-cfr-172-178-modified-hop-extract", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-modified-hop-extract/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.560 Modified hop extract. The food additive modified hop extract may be safely used in beer in accordance with the following prescribed conditions: ( a ) The food additive is used or intended for use as a flavoring agent in the brewing of beer. ( b ) The food additive is manufactured by one of the following processes:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Monoglyceride citrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.832", "use_conditions": "as a synergist and solubilizer for antioxidants in oils and fats, when used in accordance with the conditions prescribed in this section.", "id": "us-fda-21-cfr-172-178-monoglyceride-citrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-monoglyceride-citrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.832 Monoglyceride citrate. A food additive that is a mixture of glyceryl monooleate and its citric acid monoester manufactured by the reaction of glyceryl monooleate with citric acid under controlled conditions may be safely used as a synergist and solubilizer for antioxidants in oils and fats, when used in accordance with the conditions prescribed in this section.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Morpholine", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.235", "use_conditions": "as a component of food, subject to the following restrictions.", "id": "us-fda-21-cfr-172-178-morpholine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-morpholine/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.235 Morpholine. Morpholine may be safely used as a component of food, subject to the following restrictions. ( a ) It is used as the salt(s) of one or more of the fatty acids meeting the requirements of ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "N -Acetyl-L-methionine", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.372", "id": "us-fda-21-cfr-172-178-n-acetyl-l-methionine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-n-acetyl-l-methionine/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.372 N -Acetyl-L-methionine. The food additive N -acetyl-L-methionine may be safely added to food (except infant foods and foods containing added nitrites/nitrates) as a source of L-methionine for use as a nutrient in accordance with the following conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Natamycin (pimaricin)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.155", "use_conditions": "antimycotic on cheese, in amounts not to exceed 20 milligrams per kilogram (20 parts per million) in the finished product", "cas_number": "7681-93-8", "id": "us-fda-21-cfr-172-178-natamycin-pimaricin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-natamycin-pimaricin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "( b ) The additive is used as an antioxidant alone or in combination with other permitted antioxidants. ( c ) The total amount of all antioxidants added to such food shall not exceed 0.02 percent of the oil or fat content of the food, including the essential (volatile) oil content of the food. \u00a7 172.155 Natamycin (pimaricin). ( a ) Natamycin (CAS Reg. No. 7681-93-8),", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Neotame", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.829", "use_conditions": "as a sweetening agent and flavor enhancer in foods generally, except in meat and poultry, in accordance with current good manufacturing practice, in an amount not to exceed that reasonably required to accomplish the intended technical effect, in foods for which standards of identity established u...", "cas_number": "165450-17-9", "id": "us-fda-21-cfr-172-178-neotame", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-neotame/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "25, 1985] \u00a7 172.829 Neotame. ( a ) Neotame is the chemical N -[ N -(3,3-dimethylbutyl)-L-\u03b1-aspartyl]-L-phenylalanine-1-methyl ester (CAS Reg. No. 165450-17-9).", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Nicotinamide-ascorbic acid complex", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.315", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The additive is the product of the controlled reaction between ascorbic acid and nicotinamide, melting in the range 141 \u00b0C to 145 \u00b0C.", "id": "us-fda-21-cfr-172-178-nicotinamide-ascorbic-acid-complex", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-nicotinamide-ascorbic-acid-complex/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.315 Nicotinamide-ascorbic acid complex. Nicotinamide-ascorbic acid complex may be safely used in accordance with the following prescribed conditions: ( a ) The additive is the product of the controlled reaction between ascorbic acid and nicotinamide, melting in the range 141 \u00b0C to 145 \u00b0C.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Odorless light petroleum hydrocarbons", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.884", "use_conditions": "in food, in accordance with the following prescribed conditions: ( a ) The additive is a mixture of liquid hydrocarbons derived from petroleum or synthesized from petroleum gases.", "id": "us-fda-21-cfr-172-178-odorless-light-petroleum-hydrocarbons", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-odorless-light-petroleum-hydrocarbons/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.884 Odorless light petroleum hydrocarbons. Odorless light petroleum hydrocarbons may be safely used in food, in accordance with the following prescribed conditions: ( a ) The additive is a mixture of liquid hydrocarbons derived from petroleum or synthesized from petroleum gases. The additive is chiefly paraffinic, isoparaffinic, or naphthenic in nature.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Olestra", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.867", "use_conditions": "in accordance with the following conditions: ( a ) Olestra is a mixture of octa-, hepta-, and hexa-esters of sucrose with fatty acids derived from edible fats and oils or fatty acid sources that are generally recognized as safe or approved for use as food ingredients.", "id": "us-fda-21-cfr-172-178-olestra", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-olestra/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "permitted in food. [ 42 FR 14491 , Mar. 15, 1977, as amended at 47 FR 11837 , Mar. 19, 1982; 49 FR 10105 , Mar. 19, 1984; 54 FR 24897 , June 12, 1989; 70 FR 72908 , Dec. 8, 2005; 81 FR 5591 , Feb. 3, 2016; 88 FR 17721 , Mar. 24, 2023] \u00a7 172.866 Synthetic glycerin produced by the hydrogenolysis of carbohydrates. Synthetic glycerin produced by the hydrogenolysis of carbohydrates may be safely used in food, subject to the provisions of this section: ( a ) It shall contain not in excess of 0.2 percent by weight of a mixture of butanetriols. ( b ) It is used or intended for use in an amount not to exceed that reasonably required to produce its intended effect. \u00a7 172.867 Olestra. Olestra, as identified in this section, may be safely used in accordance with the following conditions: ( a ) Olestra is a mixture of octa-, hepta-, and hexa-esters of sucrose with fatty acids derived from edible fats and oils or fatty acid sources that are generally recognized as safe or approved for use as food ingredients. The chain lengths of the fatty acids are no less than 12 carbon atoms.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Oxidized polyethylene", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.260", "use_conditions": "as a component of food, subject to the following restrictions: ( a ) Oxidized polyethylene is the basic resin produced by the mild air oxidation of polyethylene.", "id": "us-fda-21-cfr-172-178-oxidized-polyethylene", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-oxidized-polyethylene/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.260 Oxidized polyethylene. Oxidized polyethylene may be safely used as a component of food, subject to the following restrictions: ( a ) Oxidized polyethylene is the basic resin produced by the mild air oxidation of polyethylene.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Oxystearin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.818", "use_conditions": "in foods, when such use is not precluded by standards of identity", "id": "us-fda-21-cfr-172-178-oxystearin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-oxystearin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive oxystearin may be safely used in foods, when such use is not precluded by standards of identity in accordance with the following conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Petrolatum", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.880", "use_conditions": "in food, subject to the provisions of this section.", "id": "us-fda-21-cfr-172-178-petrolatum", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-petrolatum/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.880 Petrolatum. Petrolatum may be safely used in food, subject to the provisions of this section. ( a ) Petrolatum complies with the specifications set forth in the United States Pharmacopeia XX (1980) for white petrolatum or in the National Formulary XV (1980) for petrolatum.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Petroleum naphtha", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.250", "use_conditions": "in food in accordance with the following conditions: ( a ) The additive is a mixture of liquid hydrocarbons, essentially paraffinic and naphthenic in nature obtained from petroleum, ( b ) The additive is refined to meet the following specifications when subjected to the procedures described i...", "id": "us-fda-21-cfr-172-178-petroleum-naphtha", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-petroleum-naphtha/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.250 Petroleum naphtha. Petroleum naphtha may be safely used in food in accordance with the following conditions: ( a ) The additive is a mixture of liquid hydrocarbons, essentially paraffinic and naphthenic in nature obtained from petroleum, ( b ) The additive is refined to meet the following specifications when subjected to the procedures described in this paragraph.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polyacrylamide", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.255", "use_conditions": "as a film former in the imprinting of soft-shell gelatin capsules when the amount used is not in excess of the minimum required to produce the intended effect.", "id": "us-fda-21-cfr-172-178-polyacrylamide", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polyacrylamide/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.255 Polyacrylamide. Polyacrylamide containing not more than 0.2 percent of acrylamide monomer may be safely used as a film former in the imprinting of soft-shell gelatin capsules when the amount used is not in excess of the minimum required to produce the intended effect.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polydextrose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.841", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) ( 1 ) Polydextrose (CAS Reg.", "cas_number": "68424-04-4", "id": "us-fda-21-cfr-172-178-polydextrose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polydextrose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "16, 2020] \u00a7 172.841 Polydextrose. Polydextrose as identified in this section may be safely used in food in accordance with the following prescribed conditions: ( a ) ( 1 ) Polydextrose (CAS Reg. No. 68424-04-4)", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polyethylene glycol (mean molecular weight 200-9,500)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.820", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) Identity.", "id": "us-fda-21-cfr-172-178-polyethylene-glycol-mean-molecular-weight-200-9-500", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polyethylene-glycol-mean-molecular-weight-200-9-500/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.820 Polyethylene glycol (mean molecular weight 200-9,500). Polyethylene glycol identified in this section may be safely used in food in accordance with the following prescribed conditions: ( a ) Identity. ( 1 ) The additive is an addition polymer of ethylene oxide and water with a mean molecular weight of 200 to 9,500.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polyglycerol esters of fatty acids", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.854", "use_conditions": "up to and including the decaglycerol esters; in food", "id": "us-fda-21-cfr-172-178-polyglycerol-esters-of-fatty-acids", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polyglycerol-esters-of-fatty-acids/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Polyglycerol esters of fatty acids, up to and including the decaglycerol esters, may be safely used in food in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polysorbate 60", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.836", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by reacting stearic acid (usually containing associated fatty acids, chiefly palmitic) with sorbitol to yield a product with a maximum acid number of 10 and a maximum water content of 0.", "id": "us-fda-21-cfr-172-178-polysorbate-60", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polysorbate-60/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.836 Polysorbate 60. The food additive polysorbate 60 (polyoxyethylene (20) sorbitan monostearate) which is a mixture of polyoxyethylene ethers of mixed partial stearic and palmitic acid esters of sorbitol anhydrides and related compounds, may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polysorbate 65", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.838", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by reacting stearic acid (usually containing associated fatty acids, chiefly palmitic) with sorbitol to yield a product with a maximum acid number of 15 and a maximum water content of 0.", "id": "us-fda-21-cfr-172-178-polysorbate-65", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polysorbate-65/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.838 Polysorbate 65. The food additive polysorbate 65 (polyoxyethylene (20) sorbitan tristearate), which is a mixture of polyoxyethylene ethers of mixed stearic acid esters of sorbitol anhydrides and related compounds, may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Polysorbate 80", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.840", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by reacting oleic acid (usually containing associated fatty acids) with sorbitol to yield a product with a maximum acid number of 7.", "id": "us-fda-21-cfr-172-178-polysorbate-80", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-polysorbate-80/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.840 Polysorbate 80. The food additive polysorbate 80 (polyoxyethylene (20) sorbitan monooleate), which is a mixture of polyoxyethylene ethers of mixed partial oleic acid esters of sorbitol anhydrides and related compounds, may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Potassium bromate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.730", "use_conditions": "in the malting of barley", "id": "us-fda-21-cfr-172-178-potassium-bromate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-potassium-bromate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive potassium bromate may be safely used in the malting of barley under the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Potassium iodide", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.375", "use_conditions": "source of essential mineral iodine; maximum intake shall not exceed 225 micrograms of iodine daily", "id": "us-fda-21-cfr-172-178-potassium-iodide", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-potassium-iodide/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive potassium iodide may be safely used in accordance with the following prescribed conditions: ( a ) Potassium iodide may be safely added to a food as a source of the essential mineral iodine", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Potassium nitrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.160", "use_conditions": "curing agent in the processing of cod roe, in an amount not to exceed 200 parts per million of the finished roe", "id": "us-fda-21-cfr-172-178-potassium-nitrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-potassium-nitrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.160 Potassium nitrate. The food additive potassium nitrate may be safely used as a curing agent in the processing of cod roe, in an amount not to exceed 200 parts per million of the finished roe.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Propylene glycol alginate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.858", "cas_number": "9005-37-2", "id": "us-fda-21-cfr-172-178-propylene-glycol-alginate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-propylene-glycol-alginate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.858 Propylene glycol alginate. The food additive propylene glycol alginate (CAS Reg. No. 9005-37-2) may be used as an emulsifier, flavoring adjuvant, formulation aid, stabilizer, surfactant, or thickener in foods in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Propylene glycol mono- and diesters of fats and fatty acids", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.856", "use_conditions": "in food, subject to the following prescribed conditions: ( a ) They are produced from edible fats and/or fatty acids in compliance with ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Quaternary ammonium chloride combination", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.165", "use_conditions": "antimicrobial agent in raw sugar cane juice, added prior to clarification when further processing must be delayed", "id": "us-fda-21-cfr-172-178-quaternary-ammonium-chloride-combination", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-quaternary-ammonium-chloride-combination/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "Permitted for Direct Addition to Food for Human Consumption Subpart B Previous Next Top Table of Contents Enhanced Content - Table of Contents Subpart B | Food Preservatives | 172.105 \u2013 172.190 | \u00a7 172.105 | Anoxomer. | \u00a7 172.110 | BHA. | \u00a7 172.115 | BHT. | \u00a7 172.120 | Calcium disodium EDTA. | \u00a7 172.130 | Dehydroacetic acid. | \u00a7 172.133 | Dimethyl dicarbonate. | \u00a7 172.135 | Disodium EDTA. | \u00a7 172.140 | Ethoxyquin. | \u00a7 172.145 | Heptylparaben. | \u00a7 172.150 | 4-Hydroxymethyl-2,6-di- tert -butylphenol. | \u00a7 172.155 | Natamycin (pimaricin). | \u00a7 172.160 | Potassium nitrate. | \u00a7 172.165 | Quaternary ammonium chloride combination.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Quinine", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.575", "use_conditions": "in food in accordance with the following conditions: Uses | Limitations | In carbonated beverages as a flavor | Not to exceed 83 parts per million, as quinine.", "id": "us-fda-21-cfr-172-178-quinine", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-quinine/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.575 Quinine. Quinine, as the hydrochloride salt or sulfate salt, may be safely used in food in accordance with the following conditions: Uses | Limitations |", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Rice bran wax", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.890", "use_conditions": "in food in accordance with the following conditions: ( a ) It is the refined wax obtained from rice bran and meets the following specifications: Melting point 75 \u00b0C to 80 \u00b0C.", "id": "us-fda-21-cfr-172-178-rice-bran-wax", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-rice-bran-wax/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.890 Rice bran wax. Rice bran wax may be safely used in food in accordance with the following conditions: ( a ) It is the refined wax obtained from rice bran and meets the following specifications: Melting point 75 \u00b0C to 80 \u00b0C.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Safrole-free extract of sassafras", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.580", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The additive is the aqueous extract obtained from the root bark of the plant Sassafras albidum (Nuttall) Nees (Fam.", "id": "us-fda-21-cfr-172-178-safrole-free-extract-of-sassafras", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-safrole-free-extract-of-sassafras/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.580 Safrole-free extract of sassafras. The food additive safrole-free extract of sassafras may be safely used in accordance with the following prescribed conditions: ( a ) The additive is the aqueous extract obtained from the root bark of the plant Sassafras albidum (Nuttall) Nees (Fam. Lauraceae).", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Salts of carrageenan", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.626", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive consists of carrageenan, meeting the provisions of ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Salts of furcelleran", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.660", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The food additive consists of furcelleran, meeting the provisions of ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Silver nitrate and hydrogen peroxide solution", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.167", "use_conditions": "antimicrobial agent in bottled water; silver not to exceed 17 micrograms per kilogram, hydrogen peroxide not to exceed 23 milligrams per kilogram", "id": "us-fda-21-cfr-172-178-silver-nitrate-and-hydrogen-peroxide-solution", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-silver-nitrate-and-hydrogen-peroxide-solution/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "Permitted for Direct Addition to Food for Human Consumption Subpart B Previous Next Top Table of Contents Enhanced Content - Table of Contents Subpart B | Food Preservatives | 172.105 \u2013 172.190 | \u00a7 172.105 | Anoxomer. | \u00a7 172.110 | BHA. | \u00a7 172.115 | BHT. | \u00a7 172.120 | Calcium disodium EDTA. | \u00a7 172.130 | Dehydroacetic acid. | \u00a7 172.133 | Dimethyl dicarbonate. | \u00a7 172.135 | Disodium EDTA. | \u00a7 172.140 | Ethoxyquin. | \u00a7 172.145 | Heptylparaben. | \u00a7 172.150 | 4-Hydroxymethyl-2,6-di- tert -butylphenol. | \u00a7 172.155 | Natamycin (pimaricin). | \u00a7 172.160 | Potassium nitrate. | \u00a7 172.165 | Quaternary ammonium chloride combination. | \u00a7 172.167 | Silver nitrate and hydrogen peroxide solution.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium lauryl sulfate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.822", "use_conditions": "in food in accordance with the following conditions: ( a ) The additive meets the following specifications: ( 1 ) It is a mixture of sodium alkyl sulfates consisting chiefly of sodium lauryl sulfate [CH 2 (CH 2 ) 10 CH 2 OSO 2 Na].", "id": "us-fda-21-cfr-172-178-sodium-lauryl-sulfate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-lauryl-sulfate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.822 Sodium lauryl sulfate. The food additive sodium lauryl sulfate may be safely used in food in accordance with the following conditions: ( a ) The additive meets the following specifications: ( 1 ) It is a mixture of sodium alkyl sulfates consisting chiefly of sodium lauryl sulfate [CH 2 (CH 2 ) 10 CH 2 OSO 2 Na].", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium mono- and dimethyl naphthalene sulfonates", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.824", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The additive has a molecular weight range of 245-260.", "id": "us-fda-21-cfr-172-178-sodium-mono-and-dimethyl-naphthalene-sulfonates", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-mono-and-dimethyl-naphthalene-sulfonates/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.824 Sodium mono- and dimethyl naphthalene sulfonates. The food additive sodium mono- and dimethyl naphthalene sulfonates may be safely used in accordance with the following prescribed conditions: ( a ) The additive has a molecular weight range of 245-260.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium nitrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.170", "use_conditions": "preservative and color fixative in smoked/cured sablefish, salmon, and shad (not to exceed 500 ppm); in meat-curing preparations for home curing (not to exceed 500 ppm in finished meat product)", "id": "us-fda-21-cfr-172-178-sodium-nitrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-nitrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "Permitted for Direct Addition to Food for Human Consumption Subpart B Previous Next Top Table of Contents Enhanced Content - Table of Contents Subpart B | Food Preservatives | 172.105 \u2013 172.190 | \u00a7 172.105 | Anoxomer. | \u00a7 172.110 | BHA. | \u00a7 172.115 | BHT. | \u00a7 172.120 | Calcium disodium EDTA. | \u00a7 172.130 | Dehydroacetic acid. | \u00a7 172.133 | Dimethyl dicarbonate. | \u00a7 172.135 | Disodium EDTA. | \u00a7 172.140 | Ethoxyquin. | \u00a7 172.145 | Heptylparaben. | \u00a7 172.150 | 4-Hydroxymethyl-2,6-di- tert -butylphenol. | \u00a7 172.155 | Natamycin (pimaricin). | \u00a7 172.160 | Potassium nitrate. | \u00a7 172.165 | Quaternary ammonium chloride combination. | \u00a7 172.167 | Silver nitrate and hydrogen peroxide solution. | \u00a7 172.170 | Sodium nitrate.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium nitrite", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.175", "use_conditions": "color fixative in smoked cured tunafish (not to exceed 10 ppm); preservative and color fixative in smoked/cured sablefish, salmon, shad (not to exceed 200 ppm); in meat-curing preparations for home curing (not to exceed 200 ppm in finished meat product)", "id": "us-fda-21-cfr-172-178-sodium-nitrite", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-nitrite/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "Permitted for Direct Addition to Food for Human Consumption Subpart B Previous Next Top Table of Contents Enhanced Content - Table of Contents Subpart B | Food Preservatives | 172.105 \u2013 172.190 | \u00a7 172.105 | Anoxomer. | \u00a7 172.110 | BHA. | \u00a7 172.115 | BHT. | \u00a7 172.120 | Calcium disodium EDTA. | \u00a7 172.130 | Dehydroacetic acid. | \u00a7 172.133 | Dimethyl dicarbonate. | \u00a7 172.135 | Disodium EDTA. | \u00a7 172.140 | Ethoxyquin. | \u00a7 172.145 | Heptylparaben. | \u00a7 172.150 | 4-Hydroxymethyl-2,6-di- tert -butylphenol. | \u00a7 172.155 | Natamycin (pimaricin). | \u00a7 172.160 | Potassium nitrate. | \u00a7 172.165 | Quaternary ammonium chloride combination. | \u00a7 172.167 | Silver nitrate and hydrogen peroxide solution. | \u00a7 172.170 | Sodium nitrate. | \u00a7 172.175 | Sodium nitrite.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium stearoyl lactylate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.846", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive, which is a mixture of sodium salts of stearoyl lactylic acids and minor proportions of sodium salts of related acids, is manufactured by the reaction of stearic acid and lactic acid and conversion to the sodium ...", "cas_number": "25-383-997", "id": "us-fda-21-cfr-172-178-sodium-stearoyl-lactylate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-stearoyl-lactylate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.846 Sodium stearoyl lactylate. The food additive sodium stearoyl lactylate (CAS Reg. No. 25-383-997) may be safely used in food in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sodium stearyl fumarate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.826", "use_conditions": "in food in accordance with the following conditions: ( a ) It contains not less than 99 percent sodium stearyl fumarate calculated on the anhydrous basis, and not more than 0.", "id": "us-fda-21-cfr-172-178-sodium-stearyl-fumarate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sodium-stearyl-fumarate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.826 Sodium stearyl fumarate. Sodium stearyl fumarate may be safely used in food in accordance with the following conditions: ( a ) It contains not less than 99 percent sodium stearyl fumarate calculated on the anhydrous basis, and not more than 0.25 percent sodium stearyl maleate.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sorbitan monostearate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.842", "use_conditions": "in or on food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by reacting stearic acid (usually containing associated fatty acids, chiefly palmitic) with sorbitol to yield essentially a mixture of esters.", "id": "us-fda-21-cfr-172-178-sorbitan-monostearate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sorbitan-monostearate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] \u00a7 172.842 Sorbitan monostearate. The food additive sorbitan monostearate, which is a mixture of partial stearic and palmitic acid esters of sorbitol anhydrides, may be safely used in or on food in accordance with the following prescribed conditions: ( a ) The food additive is manufactured by reacting stearic acid (usually containing associated fatty acids, chiefly palmitic) with sorbitol to yield essentially a mixture of esters. ( b ) The food additive meets the following specifications:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Stannous chloride", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.180", "use_conditions": "color retention in asparagus packed in glass, with lids lined with an inert material, in an amount not to exceed 20 parts per million calculated as tin (Sn)", "id": "us-fda-21-cfr-172-178-stannous-chloride", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-stannous-chloride/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "\u00a7 172.180 Stannous chloride. The food additive stannous chloride may be safely used for color retention in asparagus packed in glass, with lids lined with an inert material, in an amount not to exceed 20 parts per million calculated as tin (Sn).", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Stearyl monoglyceridyl citrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.755", "use_conditions": "in food in accordance with the following provisions: ( a ) The additive is prepared by controlled chemical reaction of the following: Reactant | Limitations | Citric acid | | Monoglycerides of fatty acids | Prepared by the glycerolysis of edible fats and oils or derived from fatty...", "id": "us-fda-21-cfr-172-178-stearyl-monoglyceridyl-citrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-stearyl-monoglyceridyl-citrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.755 Stearyl monoglyceridyl citrate. The food additive stearyl monoglyceridyl citrate may be safely used in food in accordance with the following provisions: ( a ) The additive is prepared by controlled chemical reaction of the following: Reactant |", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Succinylated monoglycerides", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.830", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is a mixture of semi-and neutral succinic acid esters of mono- and diglycerides produced by the succinylation of a product obtained by the glycerolysis of edible fats and oils, or by the direct esterification of ...", "id": "us-fda-21-cfr-172-178-succinylated-monoglycerides", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-succinylated-monoglycerides/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] \u00a7 172.830 Succinylated monoglycerides. The food additive succinylated monoglycerides may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is a mixture of semi-and neutral succinic acid esters of mono- and diglycerides produced by the succinylation of a product obtained by the glycerolysis of edible fats and oils, or by the direct esterification of glycerol with edible fat-forming fatty acids. ( b ) The additive meets the following specifications: Succinic acid content: 14.8%-25.6% Melting point: 50 \u00b0C-60 \u00b0C. Acid number: 70-120 ( c ) The additive is used or intended for use in the following foods: ( 1 ) As an emulsifier in liquid and plastic shortenings at a level not to exceed 3 percent by weight of the shortening. ( 2 ) As a dough conditioner in bread baking, when such use is permitted by an appropriate food standard, at a level not to exceed 0.5 percent by weight of the flour used.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Succistearin (stearoyl propylene glycol hydrogen succinate)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.765", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is the reaction product of succinic anhydride, fully hydrogenated vegetable oil (predominantly C 16 or C 18 fatty acid chain length), and propylene glycol.", "id": "us-fda-21-cfr-172-178-succistearin-stearoyl-propylene-glycol-hydrogen-succinate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-succistearin-stearoyl-propylene-glycol-hydrogen-succinate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.765 Succistearin (stearoyl propylene glycol hydrogen succinate). The food additive succistearin (stearoyl propylene glycol hydrogen succinate) may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is the reaction product of succinic anhydride, fully hydrogenated vegetable oil (predominantly C 16 or C 18 fatty acid chain length), and propylene glycol. ( b ) The additive meets the following specifications:", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sucralose", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.831", "cas_number": "56038-13-2", "id": "us-fda-21-cfr-172-178-sucralose", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sucralose/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "( 2 ) As a dough conditioner in bread baking, when such use is permitted by an appropriate food standard, at a level not to exceed 0.5 percent by weight of the flour used. \u00a7 172.831 Sucralose. ( a ) Sucralose is the chemical 1,6-dichloro-1,6-dideoxy-\u03b2-D-fructofuranosyl-4-chloro-4-deoxy-\u03b1-D-galactopyranoside (CAS Reg. No. 56038-13-2).", "verified_fields": [ "additive_name", "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sucrose acetate isobutyrate (SAIB)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.833", "use_conditions": "in foods in accordance with the following prescribed conditions: ( a ) Sucrose acetate isobutyrate (CAS Reg.", "cas_number": "27216-37-1", "id": "us-fda-21-cfr-172-178-sucrose-acetate-isobutyrate-saib", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sucrose-acetate-isobutyrate-saib/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.833 Sucrose acetate isobutyrate (SAIB). Sucrose acetate isobutyrate may be safely used in foods in accordance with the following prescribed conditions: ( a ) Sucrose acetate isobutyrate (CAS Reg. No. 27216-37-1), or SAIB, is the chemical alpha -D-glucopyranoside, O-acetyl-tris-O-(2-methyl-1-oxopropyl)- beta -D-fructofuranosyl, acetate tris(2-methyl propanoate).", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sucrose fatty acid esters", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.859", "use_conditions": "in accordance with the following prescribed conditions: ( a ) Sucrose fatty acid esters are the mono-, di-, and tri-esters of sucrose with fatty acids and are derived from sucrose and edible tallow or hydrogenated edible tallow or edible vegetable oils.", "id": "us-fda-21-cfr-172-178-sucrose-fatty-acid-esters", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sucrose-fatty-acid-esters/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Sucrose fatty acid esters identified in this section may be safely used in accordance with the following prescribed conditions: ( a ) Sucrose fatty acid esters are the mono-, di-, and tri-esters of sucrose with fatty acids and are derived from sucrose and edible tallow or hydrogenated edible tallow or edible vegetable oils.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sucrose oligoesters", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.869", "use_conditions": "in accordance with the following conditions: ( a ) Sucrose oligoesters consist of mixtures of sucrose fatty acid esters with an average degree of esterification ranging from four to seven.", "id": "us-fda-21-cfr-172-178-sucrose-oligoesters", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sucrose-oligoesters/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.869 Sucrose oligoesters. Sucrose oligoesters, as identified in this section, may be safely used in accordance with the following conditions: ( a ) Sucrose oligoesters consist of mixtures of sucrose fatty acid esters with an average degree of esterification ranging from four to seven.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sugar beet extract flavor base", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.585", "use_conditions": "in food in accordance with the provisions of this section.", "id": "us-fda-21-cfr-172-178-sugar-beet-extract-flavor-base", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sugar-beet-extract-flavor-base/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.585 Sugar beet extract flavor base. Sugar beet extract flavor base may be safely used in food in accordance with the provisions of this section.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Sulfated butyl oleate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.270", "use_conditions": "in food, subject to the following prescribed conditions: ( a ) The additive is prepared by sulfation, using concentrated sulfuric acid, of a mixture of butyl esters produced by transesterification of an edible vegetable oil using 1-butanol.", "id": "us-fda-21-cfr-172-178-sulfated-butyl-oleate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-sulfated-butyl-oleate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.270 Sulfated butyl oleate. Sulfate butyl oleate may be safely used in food, subject to the following prescribed conditions: ( a ) The additive is prepared by sulfation, using concentrated sulfuric acid, of a mixture of butyl esters produced by transesterification of an edible vegetable oil using 1-butanol.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Synthetic fatty alcohols", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.864", "use_conditions": "in food and in the synthesis of food components in accordance with the following prescribed conditions: ( a ) The food additive consists of any one of the following fatty alcohols: ( 1 ) Hexyl, octyl, decyl, lauryl, myristyl, cetyl, and stearyl; manufactured by fractional distillation of alco...", "id": "us-fda-21-cfr-172-178-synthetic-fatty-alcohols", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-synthetic-fatty-alcohols/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.864 Synthetic fatty alcohols. Synthetic fatty alcohols may be safely used in food and in the synthesis of food components in accordance with the following prescribed conditions: ( a ) The food additive consists of any one of the following fatty alcohols:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Synthetic glycerin produced by the hydrogenolysis of carbohydrates", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.866", "use_conditions": "in food, subject to the provisions of this section: ( a ) It shall contain not in excess of 0.", "id": "us-fda-21-cfr-172-178-synthetic-glycerin-produced-by-the-hydrogenolysis-of-carbohydrates", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-synthetic-glycerin-produced-by-the-hydrogenolysis-of-carbohydrates/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.866 Synthetic glycerin produced by the hydrogenolysis of carbohydrates. Synthetic glycerin produced by the hydrogenolysis of carbohydrates may be safely used in food, subject to the provisions of this section: ( a ) It shall contain not in excess of 0.2 percent by weight of a mixture of butanetriols.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Synthetic isoparaffinic petroleum hydrocarbons", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.882", "use_conditions": "in food, in accordance with the following conditions: ( a ) They are produced by synthesis from petroleum gases and consist of a mixture of liquid hydrocarbons meeting the following specifications: Boiling point 93-260 \u00b0C as determined by ASTM method D86-82, \u201cStandard Method for Distillation ...", "id": "us-fda-21-cfr-172-178-synthetic-isoparaffinic-petroleum-hydrocarbons", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-synthetic-isoparaffinic-petroleum-hydrocarbons/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.882 Synthetic isoparaffinic petroleum hydrocarbons. Synthetic isoparaffinic petroleum hydrocarbons may be safely used in food, in accordance with the following conditions: ( a ) They are produced by synthesis from petroleum gases and consist of a mixture of liquid hydrocarbons meeting the following specifications:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Synthetic paraffin and succinic derivatives", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.275", "use_conditions": "as a component of food, subject to the following restrictions: ( a ) The additive is prepared with 50 percent Fischer-Tropsch process synthetic paraffin, meeting the definition and specifications of ", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Synthetic petroleum wax", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.888", "use_conditions": "in or on foods in accordance with the following conditions: ( a ) Synthetic petroleum wax is a mixture of solid hydrocarbons, paraffinic in nature, prepared by either catalytic polymerization of ethylene or copolymerization of ethylene with linear (C 3 to C 12 ) alpha-olefins, and refined to me...", "id": "us-fda-21-cfr-172-178-synthetic-petroleum-wax", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-synthetic-petroleum-wax/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "( c ) Synthetic petroleum wax has a number average molecular weight of not less than 500 nor greater than 1,200 as determined by vapor pressure osmometry. ( d ) Synthetic petroleum wax may contain any antioxidant permitted", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "TBHQ (tertiary butylhydroquinone)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.185", "use_conditions": "antioxidant alone or in combination with BHA and/or BHT; total antioxidant content will not exceed 0.02 percent of the oil or fat content of the food", "cas_number": "1948-33-0", "id": "us-fda-21-cfr-172-178-tbhq-tertiary-butylhydroquinone", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-tbhq-tertiary-butylhydroquinone/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "The food additive TBHQ, which is the chemical 2-(1,1-dimethylethyl)-1,4-benzenediol (Chemical Abstracts Service Registry Number 1948-33-0), also known as tertiary butylhydroquinone, may be safely used in food in accordance with the following prescribed conditions", "verified_fields": [ "cas_number" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Terpene resin", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.280", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The food additive is the betapinene polymer obtained by polymerizing terpene hydrocarbons derived from wood.", "id": "us-fda-21-cfr-172-178-terpene-resin", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-terpene-resin/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.280 Terpene resin. The food additive terpene resin may be safely used in accordance with the following prescribed conditions: ( a ) The food additive is the betapinene polymer obtained by polymerizing terpene hydrocarbons derived from wood.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "THBP (2,4,5-trihydroxybutyrophenone)", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.190", "use_conditions": "antioxidant alone or in combination with other permitted antioxidants; total antioxidant content will not exceed 0.02 percent of the oil or fat content of the food", "id": "us-fda-21-cfr-172-178-thbp-2-4-5-trihydroxybutyrophenone", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-thbp-2-4-5-trihydroxybutyrophenone/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B", "source_quote": "The food additive THBP (2,4,5-trihydroxybutyrophenone) may be safely used in food in accordance with the following prescribed conditions: ( a ) The food additive has a melting point of 149 \u00b0C-153 \u00b0C. ( b ) It is used as an antioxidant alone or in combination with other permitted antioxidants.", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Vitamin D 2", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.379", "id": "us-fda-21-cfr-172-178-vitamin-d-2", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-vitamin-d-2/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.379 Vitamin D 2 . Vitamin D 2 may be used safely in foods as a nutrient supplement defined under \u00a7 170.3(o)(20) of this chapter in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Vitamin D 3", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.380", "id": "us-fda-21-cfr-172-178-vitamin-d-3", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-vitamin-d-3/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.380 Vitamin D 3 . Vitamin D 3 may be used safely in foods as a nutrient supplement defined under \u00a7 170.3(o)(20) of this chapter in accordance with the following prescribed conditions:", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Vitamin D2 bakers yeast", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.381", "use_conditions": "source of vitamin D2 and as a leavening agent", "id": "us-fda-21-cfr-172-178-vitamin-d2-bakers-yeast", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-vitamin-d2-bakers-yeast/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Vitamin D 2 bakers yeast may be used safely in foods as a source of vitamin D 2 and as a leavening agent in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Vitamin D2 mushroom powder", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.382", "use_conditions": "source of vitamin D2", "id": "us-fda-21-cfr-172-178-vitamin-d2-mushroom-powder", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-vitamin-d2-mushroom-powder/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "Vitamin D 2 mushroom powder may be used safely in foods as a source of vitamin D 2 in accordance with the following prescribed conditions", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Whole fish protein concentrate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.385", "use_conditions": "food supplement; derived from whole, wholesome hake and hakelike fish, herring, menhaden, and anchovy", "id": "us-fda-21-cfr-172-178-whole-fish-protein-concentrate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-whole-fish-protein-concentrate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive whole fish protein concentrate may be safely used as a food supplement in accordance with the following prescribed conditions", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Xanthan gum", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.695", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is a polysaccharide gum derived from Xanthomonas campestris by a pure-culture fermentation process and purified by recovery with isopropyl alcohol.", "id": "us-fda-21-cfr-172-178-xanthan-gum", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-xanthan-gum/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "24, 2023] \u00a7 172.695 Xanthan gum. The food additive xanthan gum may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is a polysaccharide gum derived from Xanthomonas campestris by a pure-culture fermentation process and purified by recovery with isopropyl alcohol.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Xylitol", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.395", "use_conditions": "in foods for special dietary uses, provided the amount used is not greater than that required to produce its intended effect.", "id": "us-fda-21-cfr-172-178-xylitol", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-xylitol/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.395 Xylitol. Xylitol may be safely used in foods for special dietary uses, provided the amount used is not greater than that required to produce its intended effect.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Yeast-malt sprout extract", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.590", "use_conditions": "in food in accordance with the following prescribed conditions: ( a ) The additive is produced by partial hydrolysis of yeast extract (derived from Saccharomyces cereviseae, Saccharomyces fragilis, or Candida utilis ) using the sprout portion of malt barley as the source of enzymes.", "id": "us-fda-21-cfr-172-178-yeast-malt-sprout-extract", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-yeast-malt-sprout-extract/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.590 Yeast-malt sprout extract. Yeast-malt sprout extract, as described in this section, may be safely used in food in accordance with the following prescribed conditions: ( a ) The additive is produced by partial hydrolysis of yeast extract (derived from Saccharomyces cereviseae, Saccharomyces fragilis, or Candida utilis ) using the sprout portion of malt barley as the source of enzymes. The additive contains a maximum of 6 percent 5\u2032 nucleotides by weight.", "verified_fields": [ "additive_name", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Yellow prussiate of soda", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.490", "use_conditions": "anticaking agent in salt and adjuvant in production of dendritic crystals of salt", "id": "us-fda-21-cfr-172-178-yellow-prussiate-of-soda", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-yellow-prussiate-of-soda/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "The food additive yellow prussiate of soda (sodium ferrocyanide decahydrate; Na 4 Fe(CN) 6", "verified_fields": [ "additive_name" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] }, { "additive_name": "Zinc methionine sulfate", "jurisdiction": "US FDA (21 CFR 172\u2013178)", "status": "permitted", "regulatory_citation": "21 CFR 172.399", "use_conditions": "in accordance with the following prescribed conditions: ( a ) The additive is the product of the reaction between equimolar amounts of zinc sulfate and DL-methionine in purified water.", "cas_number": "56329-42-1", "id": "us-fda-21-cfr-172-178-zinc-methionine-sulfate", "url": "https://referencesource.org/food-additive-approval-status-us-vs-eu/us-fda-21-cfr-172-178-zinc-methionine-sulfate/", "source": "https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172", "source_quote": "\u00a7 172.399 Zinc methionine sulfate. Zinc methionine sulfate, CAS Reg. No. 56329-42-1, may be safely used in accordance with the following prescribed conditions: ( a ) The additive is the product of the reaction between equimolar amounts of zinc sulfate and DL-methionine in purified water.", "verified_fields": [ "additive_name", "cas_number", "use_conditions" ], "derived_fields": [ "jurisdiction", "regulatory_citation", "status" ] } ] }