# Federal Register 2026-21051 — effective 2026-12-14 — Significant New Use Rules on Certain Chemical Substances (26-1) — Environmental Protection Agency For Federal Register 2026-21051, effective date is 2026-12-14; agency is Environmental Protection Agency; published is 2026-10-15; cfr parts amended is 40 CFR 721, recorded from its source on 2026-10-19; source re-checked 2026-11-03. - **FR document number:** 2026-21051 _(verified: appears in the quote below)_ - **Rule:** Significant New Use Rules on Certain Chemical Substances (26-1) _(verified: appears in the quote below)_ - **Agency:** Environmental Protection Agency _(verified: appears in the quote below)_ - **Effective date:** 2026-12-14 _(verified: appears in the quote below)_ - **DATES, as printed:** This rule is effective on December 14, 2026. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on October 29, 2026. _(verified: appears in the quote below)_ - **CFR parts amended:** 40 CFR 721 _(our reading, not quoted from the source)_ - **Published:** 2026-10-15 _(verified: appears in the quote below)_ ## What the source says > {"document_number":"2026-21051","title":"Significant New Use Rules on Certain Chemical Substances (26-1)","agency_names":["Environmental Protection Agency"],"effective_on":"2026-12-14","dates":"This rule is effective on December 14, 2026. For purposes of judicial review, this rule shall be promulgated at 1 p.m. (EST) on October 29, 2026.","cfr_references":[{"chapter":null,"citation_url":null,"part":"721","title":40}],"publication_date":"2026-10-15","html_url":"https://www.federalregister.gov/documents/2026/10/15/2026-21051/significant-new-use-rules-on-certain-chemical-substances-26-1"} ## Source - https://www.federalregister.gov/api/v1/documents.json?per_page=1000&order=oldest&conditions%5Btype%5D%5B%5D=RULE&conditions%5Beffective_date%5D%5Bgte%5D=2026-08-31&conditions%5Beffective_date%5D%5Blte%5D=2026-12-31&fields%5B%5D=document_number&fields%5B%5D=title&fields%5B%5D=agency_names&fields%5B%5D=effective_on&fields%5B%5D=dates&fields%5B%5D=cfr_references&fields%5B%5D=publication_date&fields%5B%5D=html_url Last verified: 2026-11-03. Review by: 2026-11-16. Part of [Federal rules taking effect: every US final rule in the Federal Register, by effective date](https://referencesource.org/federal-rules-taking-effect/).