# Federal Register 2026-22208 — effective 2026-10-30 — Schedules of Controlled Substances: Placement of Centanafadine in Schedule III — Drug Enforcement Administration

For Federal Register 2026-22208, effective date is 2026-10-30; agency is Drug Enforcement Administration; published is 2026-10-30; cfr parts amended is 21 CFR 1308, recorded from its source on 2026-11-02; source re-checked 2026-11-03.

- **FR document number:** 2026-22208 _(verified: appears in the quote below)_
- **Rule:** Schedules of Controlled Substances: Placement of Centanafadine in Schedule III _(verified: appears in the quote below)_
- **Agency:** Drug Enforcement Administration _(verified: appears in the quote below)_
- **Effective date:** 2026-10-30 _(verified: appears in the quote below)_
- **DATES, as printed:** This rule is effective October 30, 2026. Comments must be submitted electronically or postmarked on or before November 30, 2026. The electronic Federal Docket Management System will not accept comments after 11:59 p.m. Eastern Time on the last day of the comment period. _(verified: appears in the quote below)_
- **CFR parts amended:** 21 CFR 1308 _(our reading, not quoted from the source)_
- **Published:** 2026-10-30 _(verified: appears in the quote below)_

## What the source says

> {"document_number":"2026-22208","title":"Schedules of Controlled Substances: Placement of Centanafadine in Schedule III","agency_names":["Justice Department","Drug Enforcement Administration"],"effective_on":"2026-10-30","dates":"This rule is effective October 30, 2026. Comments must be submitted electronically or postmarked on or before November 30, 2026. The electronic Federal Docket Management System will not accept comments after 11:59 p.m. Eastern Time on the last day of the comment period.","cfr_references":[{"chapter":null,"citation_url":null,"part":"1308","title":21}],"publication_date":"2026-10-30","html_url":"https://www.federalregister.gov/documents/2026/10/30/2026-22208/schedules-of-controlled-substances-placement-of-centanafadine-in-schedule-iii"}

## Source

- https://www.federalregister.gov/api/v1/documents.json?per_page=1000&order=oldest&conditions%5Btype%5D%5B%5D=RULE&conditions%5Beffective_date%5D%5Bgte%5D=2026-08-31&conditions%5Beffective_date%5D%5Blte%5D=2026-12-31&fields%5B%5D=document_number&fields%5B%5D=title&fields%5B%5D=agency_names&fields%5B%5D=effective_on&fields%5B%5D=dates&fields%5B%5D=cfr_references&fields%5B%5D=publication_date&fields%5B%5D=html_url

Last verified: 2026-11-03. Review by: 2026-11-16.
Part of [Federal rules taking effect: every US final rule in the Federal Register, by effective date](https://referencesource.org/federal-rules-taking-effect/).